:,;? 



Influence of Inanition on Metabolism. 



third day of experiments Nos. 70 and 76 there was an increase over the second, 

 while on the third day of experiment No. 74 there were but 5 grams of protein 

 lost. For all the experiments there was an average loss per day of about 19 

 grams of protein. 



During experiment No. 70 the body stored fat in considerable amounts on 

 the first day, but stored much less on the second day, and none on the third. 

 In the 1-day experiment, No. 72, there were 25.8 grams of fat lost. Experi- 

 ment No. 74 showed a slight loss on the first day and substantial gains on the 

 2 succeeding days with an average gain for the whole experiment of about 9 

 grams per day. In experiment No. 76 there was a marked loss of fat on the 

 first day, a loss of about 25 grams on the second, and a gain of about 10 

 grams on the third, the average loss being a little more than 25 grams per day. 



Table 255. Protein, fat, carbohydrates, preformed water, and energy gained or 

 lost in metabolism experiments with food. 



Experi- 

 ment 

 number. 



Subject and date 

 of experiments. 



Protein, 



gain (+) 



or loss ( ), 



Fat, 



gain (+) 



or loss ( ). 



Carbohy- 

 drates, 

 gain (+) 

 or loss ( ). 



Pre- 

 formed 

 water, 

 gain(+) 

 or loss ( ). 



Energy, 



gain (+) 



or loss ( ) 



70... 



72... 



74... 



76.. 



A.L.L., 1904: 

 Dec. 20-21 . 

 Dec. 21-22. 

 Dec. 33-23. 



Average per day. 



S.A.B., 

 Jan. 



1905 

 11.. 



S.A.B., 1905: 

 Feb. 2-3.. 

 Feb. 3-4. 

 Feb. 4-5.. 



Average per day. 



.A.B., 1905: 



Mar. 11-12 



Mar. 12-13 



Mar. 13-14 



Average per day. 



Orams. 



29.16 



9.60 



11.64 



Orams. 

 + 34.06 

 + 4.68 

 - .40 



Grams. 

 + 16.64 



+ 30.57 

 20 90 



16.80 +12.78 | + 



Orams. 

 160.3 

 -203.6 

 + 149.6 



.77 - 71.5 



Cals. 

 + 213 

 + 131 

 121 



+ 74 



-30.66 



-25.78 



+ 61.99 



i- 37.7 



-108 



-28.74 

 -13.80 

 -4.98 



- 4.50 

 + 31.45 

 + 9.57 



+ 103.70 

 + 43.53 

 + 56.37 



-15.84 + 8.84 + 67.83 + 95.3 



+ 52.2 

 + 106.1 



+ 127.4 



+ 289 

 + 415 

 + 400 



+ 36S 



-30.84 

 -12.72 

 -16.74 



-20.10 



-310 



112 



140 



-154 



1 Water of feces taken into account. 



The carbohydrate balance shows that on only 2 days of this series of experi- 

 ments was there a loss of glycogen to the body. On the last day of experi- 

 ments Nos. 70 and 76 there was a loss of 21 and 27 grams, respectively. This 

 gain of glycogen in an organism which had previously been deprived of glyco- 

 gen indicates strongly the tendency of the body to replace its lost glycogen. 

 On the first days of experiments Nos. 74 and 76, respectively, there were over 

 100 grams of glycogen gained. The relation of the gain or loss of glycogen 

 to the gain or loss of protein is extremely interesting. Thus, aside from the 



