5 1 2 Influence of Inanition on Metabolism. 



hand, the nitrogen-sulphur ratio would imply that a large proportion of the 

 nitrogen was stored in the body in the form of a protein with a composition 

 approximating that of flesh protein. 



Eichter m noticed a daily gain of nitrogen amounting to 12 grams in a 17- 

 day experiment with a patient who had suffered from oesophagus stricture. 

 Luthje and Berger, 178 experimenting with a healthy man, secured a storage of 

 nitrogen amounting to over 10 grams per day for over a week. In this experi- 

 ment the calcium oxide and phosphorus pentoxide were also determined, and 

 hence the amount of phosphorus available for the formation of flesh 

 calculated. 178 



In studying a woman who was much reduced by worry, sleeplessness, and 

 neglect of food, but otherwise organically sound, White & Spriggs I8 suc- 

 ceeded in securing a storage of nitrogen amounting to 661 grams in 55 days. 



A large increase in the nitrogenous material in the liver of animals fed after 

 fasting was noted by Pugliese m and by Seitz,* 2 who, likewise, observed that 

 the increase in the protein of the liver was paralleled by an increase in the gly- 

 cogen content. 



In the experiments here reported with food following fast, while showing 

 marked gains of nitrogen, sulphur, and phosphorus, the data are insufficient 

 for indicating the exact nature of the material stored. 



177 Berliner klin. Wochenschr. (1904), p. 1271. 

 178 Deutsches Archiv f. klin. Medicin. (1904), 81, p. 278. 



179 An excellent discussion of the subject of the nature of the material gained after 

 fasting is given by Magnus-Levy, Physiologie des Stoffwechsels (1905). pp. 337-364. 

 U0 Journ. of Physiol. (1901), 26, p. 151. 

 181 Archiv di farmacol. e scienze affini (1904), 3, p. 185. 

 182 Archiv f. g. Physiologie (1906), 111, p. 309. 



