GENERAL PROPERTIES AND ACTIONS OF THE VENOM. 73 



Inl ravenous injection : Guinea-pig 63, 600 g. June 12, 9 b 52'" injected 0.05 c.c. of venom. 



10 h 05 m dying. 10 h 09 m dead. 

 Intravenous injection: Guinea-pig 54, 600 g. June 12, 10 h 16 m injected 0.02 c.c. of venom. 



Showed serious symptoms, but recovered. 

 Subcutaneous injection: Rat 71, 170 g. June 11, ll h 45 m injected 0.2 c.c. of venom. 



Showed serious symptoms for a while and continued drowsy during day. June 



12, recovered. 

 Intraperitoneal injection: Rat 75, 190 g. June 11, ll h 46 m injected 0.2 c.c. of venom. 



Serious symptoms during day. Worse than rat 71. June 12, dead. 

 Intravenous injection: Rat 79, 30 g. June 11, 3 h 01 m injected 0.2 c.c. of venom. S h 15 m 



dead. 

 Subcutaneous injection: Rat 72, 170 g. June 11, ll h 48 m injected 0.1 c.c. of venom. 



Symptoms same as Rat 71. June 12, recovered. 

 Intraperitoneal injection: Rat 76, 190 g. June 11, ll h 20'" injected 0.1 c.c. of venom. 



Serious symptoms. June 12, recovered. 

 Intravenous injection: Rat 80, 120 g. June 11, 3 h 20 m injected 0.1 c.c. of venom. 4 h 20 m 



dead. 

 Subcutaneous injection: Rat 73, 170 g. June 11, ll h 52 m injected 0.05 c.c. of venom. 



No symptoms. June 12, living. 

 Intraperitoneal injection: Rat 77, 170 g. June 11, ll h 55 m injected 0.05 c.c. of venom. 



No symptoms. June 12, living. 

 Intravenous injection: Rat 81, 130 g. June 11, 5 h 15 m injected 0.05 c.c. of venom. 



6 h 00 m dead. 

 Subcutaneous injection: Rat 74, 170 g. June 11, // h 55 m injected 0.02 c.c. of venom. 



No symptoms. June 12, living. 

 Intraperitoneal injection: Rat 78, 170 g. June 11, 12 b 00 m injected 0.02 c.c. of venom. 



June 12, living; no symptoms. 10 h 30 m second injection of 0.28 c.c. of venom. 



l h 30 m dead. 

 Intravenous injection: Rat 82, 125 g. June 11, 5 h 20 m injected 0.02 c.c. of venom. June 



12, living. 

 Subcutaneous injection: Guinea-pig 92, 400 g. June 21, ll h 00 m injected 0.15 c.c. of 



venom. l h 15 m dead. 

 Intraperitoneal injection: Guinea-pig 95, 300 g. June 21, 12 h 30 m injected 0.15 c.c. of 



venom. l h 15 m dead. 

 Subcutaneous injection: Rabbit A 1, 1500 g. Feb. 3, 10 h 30 m injected 15 mg. venom. 



Feb. 4, seems well. Feb. 6, dead. 

 Subdural injection: Rabbit A 2, 1500 g. Feb. 3, 2 h 30 m injected 8 mg. venom. Feb. 



4, seems well. Feb. 7, dead. 

 Stomach injection: Guinea-pig 117, 340 g. June 28, 3 h 15 m injected about 1 c.c. of venom 



in 6 c.c. NaCl. 4 h 10 m recovered from influence of ether; appears normal. 



July 1, living, normal. 

 Subcutaneous injection: Rabbit A 5, 2500 g. Feb. 3, S h 00 m injected 8 gtt. fresh venom. 



3 h 30 m affected. 5 h 00 m improved. 

 Subdural injection: Rabbit A 6, 2100 g. Feb. 5, 4 h 30 m injected 8 gtt. fresh venom. 



Feb. 6, dead. 

 Stomach injection: Rat 112, 140 g. June 28, 3 h 35 m injected 1 c.c. undiluted venom. 



Tied up stomach at point of puncture. 4 h 10 m appears well. July 1, living, 



normal. 

 Subcutaneous injection: Rabbit A 9, 1080 g. Feb. 9, 12 h 30 m injected 4 gtt. fresh 



venom. 3 h 00 m affected. 9 h 00 m dead. 

 Subdural injection: Rabbit A 10, 1100 g. Feb. 9, 12 h 45 m injected 4 gtt. fresh venom. 



l h 30 m slightly affected. Feb 10, 2 h 00 m dying; killed. 

 Stomach injection: Rat 111, 120 g. June 28, 12 h 39 m injected 1 c.c. pure venom. 



12 h 4-5 m respiration disturbed. l b 00 m improved, but remains lying down. 



2 h 00 m somewhat better. 4 h 00'" somewhat better; may live. June 27, dead. 

 Subcutaneous injection: Rabbit A 14, 1120 g. Feb. 13, 12 h 00 m injected 2 gtt. fresh 



venom. 2 h 00 m affected. 2 h 30 m dead. 

 Subdural injection: Rabbit A 13, 1120 g. Feb. 12, 12 h 00'" injected 2 gtt. fresh venom. 



2 h 00 m much affected. 4 h 4$ m dead. The symptoms produced in this experi- 

 ment we attribute to the escape of venom from the wound into the peritoneal cavity. 



With rat 117, where precautions were taken to ligature the stomach at the point 



of injection, no symptoms appeared. 

 Subdural injection: Guinea-pig 93, 400 g. June 21, ll h 20 m injected 0.15 c.c. of venom. 



ll h 28 m dead. 

 Subdural injection: Guinea-pig 94, 350 g. June 21, 12 h 05<" injected 0.1 c.c. of venom. 



12 h 13 m dead. 

 Subdural injection: Guinea-pig 96, 350 g. June 21, 12 h 05 m injected 0.1 c.c. of venom. 



2 h 45 m dies, having been almost dead since 2 h 07 m . 



