798 



POPULAR SCIENCE MONTHLY. 



The administration of alcoliol was begun May 12th, six cubic 

 centimetres of chemically pure alcohol, diluted to forty per cent 

 with water and mixed with their breakfast, being given to Tipsy 

 and Bum. No appreciable effect was produced. Accordingly, the 



18 95 



1 89 S 



Fig. 7. Growth o the Dogs. 



dose was increased daily until May 24th, when they received 

 twenty-five cubic centimetres apiece. This caused rather pro- 

 nounced intoxication, but nothing approaching stupor. Both 

 dogs appeared next morning as bright and playful as ever. 



My intention at this time was to run the experiment along the 

 line of light daily intoxication, but, with Dr. Billings's concur- 

 rence, what seemed to be a better physiological limit was adopt- 

 ed.* It was decided to give as large doses as possible, short 

 of producing noticeable symptoms of intoxication. Accordingly, 

 the amount was reduced to fifteen cubic centimetres, which was 

 increased to twenty cubic centimetres by June 10th, and thereafter, 

 as the dogs grew, up to thirty-five cubic centimetres apiece by the 



* For the suggestion as to the proper physiological limit, I am happy to acknowledge 

 my indebtedness to Mrs. Hodge. At the time when Tipsy and Bum were first intoxicated, 

 the only time they have been intoxicated, Mrs. Hodge not only suggested the physiological 

 limit, but went to considerable pains of argument to turn me from my avowed purpose of 

 " getting the greatest physiological (V) effect in the shortest time." This has been a prime 

 defect of similar work in the past, and whatever of value may attach to the present re- 

 search I consider as mainly due to this suggestion. 



