The Transportation of Pangens 203 



of this acid otherwise, than by means of definite particles, 

 which have this power, owing to their molecular consti- 

 tution, and which might best be likened to enzymes. 



There is no difficulty in assuming that these particles 

 become active only when they are made so by molecular 

 excitations from the nucleus, and I do not doubt that such 

 co-relations frequently occur. But the difficulty lies in 

 the question as to whence the cytoplasm gets these par- 

 ticles. Because, obviously, the power of forming malic 

 acid cannot be communicated by those excitations to any 

 kind of substratum. Such excitations can only set free 

 a function, and only that can be set free which is already 

 present potentially. Whence then originate the malic acid 

 formers of the cytoplasm? 



This question is not answered by the dynamic theory. 

 But, as previously stated, hybrids teach us that similar pa- 

 ternal characters can be inherited from the father, and 

 therefore be transmitted in a latent state in the sperm-nu- 

 cleus. Hence the producers of the malic acid must, them- 

 selves, be derived from the nuclei. They are simply the 

 active states of the malic acid pangens that are inactive in 

 the nucleus. And the same must evidently hold, in a 

 similar manner, of all the other hereditary factors. 



In this way, we arrive at the assumption previously 

 made, that the pangens of the cytoplasm originate from 

 the nuclei. 



Haberlandt has pointed out the possibility of an en- 

 zymatic influence of the nucleus on the cytoplasm. The 

 significance of peculiar positions of the nucleus, observed 

 by this investigator, in the vicinity of the place of most 

 vigorous cell-activity, remains, according to him, the same, 

 "if that influence should be not a dynamic, but a material 

 one, and if, consequently, a diffusion of certain chemical 



