380 PROCEEDINGS OF THE ACADEMY OF 



galvanized ; it responds to a very weak current. 3.47, injected 

 one-twentieth of a drop of conia. 3.53, the right sciatic no longer 

 responds to a weak current. 3.55, the strongest current applied 

 to the sciatic nerves barely causes movements in the tributary 

 muscles. 3.57, neither sciatic responds to the strongest current. 



Exp. 24. On a medium-sized frog. 4.45, injected one-eighth 

 drop into the abdomen. 4.55, paralysis is complete, neither of the 

 sciatic or median nerves respond to the strongest galvanic cur- 

 rent. 



Having thus determined that galvanic irritation applied to the 

 nerves of batrachians, paralyzed by conia, fails to induce contrac- 

 tions in the tributary muscles, I then proceeded to determine 

 whether or not the same loss of irritability occurs in the nerves 

 of mammals. 



Exp. 25. On a large mouse. 1.56, injected one-half drop of co- 

 nia into the peritoneum. 2.01, paralysis is complete posteriorly, 

 and paresis anteriorly. 2.05, paralysis anterior ; exposed and 

 galvanized the sciatics without producing any contractions in the 

 tributary muscles. 



Exp. 26. On a large cat. 5.10, injected six drops of the drug 

 into the peritoneum. 5.17, paralysis complete both anteriorly 

 and posteriorly. 5.17^, exposed the sciatics, they will not respond 

 to the strongest current. 



The only instances in which the sciatics continued to respond 

 after the paralysis occurred, were experiments 44 and 45, but these 

 are only mentioned as exceptions here, as further on thej' are 

 given in full with explanations. 



The following experiments were made to determine whether the 

 paralysis was cerebral or not. 



Exp. 27. The spinal cord of a large mouse was cut at the tenth 

 dorsal vertebra; irritation posterior causes reflex movements 

 in the hind extremities. 3.47^, injected one-half drop of conia 

 into the peritoneum. 3.50^, anterior paralysis ; irritation pos- 

 terior no longer causes reflex movements. The sciatics do not 

 respond to galvanism. 



Exp. 28. 1 repeated the last experiment, with similar results, on 

 a medium-sized female cat. 5.52, injected four drops into the 

 peritoneum. 6.02, paralysis anterior; reflex movements ceased 

 posterior, and at the same time the sciatic and median nerves 

 ceased to respond to galvanism. 



