NATURAL SCIENCES OP PHILADELPHIA. 



395 



Action on Temperature. 



All investigators of the action of conia have thus far agreed on 

 one point, to almost totally ignore this action of the drug. One 

 copying from the other, all saying that the temperature is lowered, 

 and, as far as I am aware, until this investigation, no one even 

 imagined that conia was so peculiar as to be one of three drugs 

 (atropia, woorara,(?) and conia) that cause a decided increase in 

 the temperature of the animals poisoned. This increase occurs 

 not 011I3' from poisonous doses, but also when full therapeutic 

 doses are administered. This increase in temparature lasts from 

 three-quarters of an hour to an hour and a half, when the temper- 

 ature gradually becomes normal. 



