OVARIAN PREGNANCY. 257 



distinct red blood-corpuscles. Most of the villi have a fibrous mesenchyme; in 

 some it is mucoid. Scattered through the mesenchyme of the chorion there are 

 blood-islands, or rather groups of blood-cells, within the blood-vessels from the 

 embryo. These are especially numerous where the villi are attached to the main 

 wall of the chorion, showing that in its development the embryo must have been 

 present at an earlier stage. The distal ends of the villi are apparently covered 

 with a double layer of epithelial cells, which is as should be in normal development. 

 However, a rich peripheral trophoblast is missing. In the trophoblast are nu- 

 merous small masses of disintegrating cells. These appear to be pretty well inter- 

 mingled with mesenchyme cells at the tips of the villi, as shown in the figure. 

 Many polymorphonuclear leucocytes are present where the trophoblast comes in 

 contact with the blood-clot. Among the leucocytes there are isolated cells of the 

 trophoblast. At points the isolated cells are also embedded in the mesenchyme 

 of the villi. Altogether, these processes are quite identical with those found in 

 the villi of the uterine moles, where there is also every indication of degeneration 

 of the villi and their trophoblast, due to either faulty implantation or to infection. 

 In none of the sections is there any indication of the embryonic mass, nor do the 

 sections which were sent show the character of the ovarian tissue adjacent to the 

 clot containing the villi, although in a number of sections the chorionic wall is 

 shown to be composed of two layers, which doubtless represent both the chorion 

 and the amnion (figure 162, Am and Ch). In one section these two layers are 

 blended for a short distance, and at this point there are numerous embryonic 

 blood-vessels. The fact that the amnion, which is quite characteristic, is in close 

 apposition with the chorion, and the presence of numerous blood-islands show 

 quite conclusively that they are identical with an ovum which is sufficiently well 

 advanced in development to contain an embryo about 15 mm. long. 



When the specimen came to us it was composed of two pieces which were 

 formed by cutting directly into it on the side of the rupture, as shown in figures 

 157 and 158. These are drawn natural size, and therefore give the dimensions of 

 the ovary. A loose piece of clot was taken out and cut into serial sections, but 

 upon close examination with a microscope no trace of the chorion could be found 

 in any of them, so it appears as though we received only the clot and a small 

 remnant of the chorion attached to it, which had possibly invaded the ovarian 

 tissue and lodged itself freely within it. The ovary was then cut into slabs about 

 5 mm. thick, and at a distance from the cavity containing the villi a large corpus 

 luteum, 10 mm. in diameter and entirely filled with blood, came into view (figure 

 159). New sections of the wall of the cavity were then made. These show that 

 the cavity as a whole is lined with a smooth, grayish membrane barely 0.5 mm. in 

 thickness. In the tissue between the corpus luteum and the main wall of the cavity 

 there is an extravasation of blood which enters a few of the adjacent Graafian 

 follicles. The arrangement of these follicles is well shown in figure 158, but the 

 corpus luteum, which is filled with blood, is much nearer the proximate pole of 

 the ovary, and is therefore not shown in this section. It is close to the point 

 marked Adh (figure 157). Sections were then cut through the whole ovary, and 



