SPECIMENS COMPOSED OF VILLI ONLY. 



109 



No. 698. 



(1) N. E. B. Iglehart, Baltimore, Maryland. 



(2) A 50X20X13 mm. Decidual cast with some 

 syncytium and trophoblast. 



(3) Patient 38 years of age, mother of three children, 

 this being her first abortion. Last period April 11 to 14; 

 abortion June 6. No history of infection. 



(4) The specimen looks like a solid irregular mole and 

 measures 50X20X13 mm. On sectioning, it is found 

 filled with blood, with a space between the inner wall and 

 the decidua. 



(5) Transverse sections of the same suggest that it is 

 composed entirely of decidua and clot. What appears to 

 be the chorionic wall is the decidua capsularis, the 

 interior of which is filled entirely with blood. Between 

 the slight traces of the chorionic wall and the blood-clot 

 containing them a few small masses of syncytium and 

 trophoblast are found. The ovum apparently has been 

 destroyed almost entirely, so that the sections remind one 

 very much of the type of pregnancy found in the uterine 

 tube. 



(6) Marked infiltration. 



No. 749. 



(1) Dr. G. C. McCormick, Sparrows Point, Maryland. 



(2) A 100X100X100 mm. 



(3) Patient aged 19 years, married five months and 

 thought she was pregnant four months. Symptoms re- 

 semble placenta prsevia. Irregular. Hemorrhage for two 

 months. 



(4) The specimen is a hydatiform mole in several pieces, 

 which, when placed together, form a large mass 100 mm. in 

 diameter. The exterior is covered with numerous wart- 

 like prominences from 1 to 3 mm. in diameter, and with 

 hypertrophic yilli, some of which are 40 mm. in length and 

 over 10 mm. in diameter. Most of these are attached to 

 the main wall of the chorion by thread-like processes. No 

 embryo was found. 



(5) The villi are very large and most of them have 

 undergone mueoid degeneration, the interior not staining 

 well by any of the methods used. The trophoblast is 

 mostly nccrotic, but at points it seems to be active. The 

 mesenchyme of some of the villi appears to be more or 

 less fibrous and contains large nests or groups of cells 

 appearing to come from degenerating blood-vessels. There 

 are also masses of Hofbauer cells in these villi, which are 

 covered by a fairly active trophoblast. 



(6) Hydatiform degeneration; decidua absent. 



No. 861. 



(1) C. W. R. Crum, Brunswick, Maryland. 



(2) A 35X25X15 mm. 



(3) Woman, aged 40, married 16 years. Eleven preg- 

 nancies: eight full-term children; abortion between first 

 and second child; two abortions since last child, now 2% 

 years old. Last menstrual period February 14 to 18 and 

 abortion March 29 following. No infection apparent in 

 condition of uterus. No venereal diseases. Family fer- 

 tile. 



(4) The specimen consists of two irregular masses which 

 measure 11X10X5 mm. and 35X17X11 mm., respec- 

 tively. The large mass is firm and at several points villi, 

 which attain a length of 7 mm., protrude from it. 



(5) These have undergone fibrous as well as mueoid 

 degeneration and are matted together by an inflammatory 

 exudate which contains great masses of leucocytes. The 

 trophoblast is scanty. 



(6) .Severe infection; some hydatiform degeneration. 



No. 866. 



(1) Thomas S. Cullen, Baltimore, Maryland. 



(2) A 26X20X9 mm. 



(3) Patient aged 36, married 17 years. Seven preg- 

 nancies: children 16, 14, 10, and 7 years; miscarriages 

 1910, 1913, and this one, March 16, 1914. Patient missed 



no menstrual period. In July 1913 there was flooding and 

 afterwards a little continuous bleeding until the abortion. 

 Last periods March 6 and one month before abortion. 

 Uterus slightly enlarged. No venereal diseases. 



(4) The specimen measures 26X20X9 mm. and is 

 covered with villi, which are so flattened over the greater 

 part of the surface as to form an almost smooth exterior, 

 but a portion of the circumference of the specimen supports 

 thin, shaggy villi from 5 to 7 mm. in length. The ovum is 

 solid, and on being cut open no chorionic cavity it apparent. 



(5) The completely degenerated villi which are outlined 

 by fibrinoid only are matted together with fibrin. The 

 extensive trophoblast is necrotic. It appears as though 

 the specimen had been completely detached for some time 

 before the abortion, and that it must be far older than 

 the history suggests. 



(6) Necrotic early confluent hydatiform degeneration. 



No. 914. 



(1) Benjamin O. McCIeary, Baltimore, Maryland. 



(2) A 40X10X10. 



(3) First pregnancy of a woman aged 24 years, married 

 in 1910. Last menstrual period May 12 to 16, 1914, and 

 abortion June 17 following. Condition of uterus negative. 

 Venereal diseases negative. Fertility of family good. 



(4) The specimen is a firm elongated abortus 40 X 10 X 10 

 mm. 



(5) It is composed of a large piece of hemorrhagic and 

 inflamed decidua, scattered through which are large 

 strands of fibrinoid substance and a few yilli which have 

 undergone mueoid degeneration. There is some tropho- 

 blast. 



(6) Marked infiltration. 



No. 920. 



(1) Hiram Fried, Baltimore, Maryland. 



(2) A 50X50X50 mm. 



(4) The specimen consists of large hemorrhagic frag- 

 ments which together constitute a mass about 100 mm. in 

 diameter. One of these fragments forms a shell 50 mm. 

 in diameter, which contains a cavity about 30 mm. in 

 diameter. 



(5) Sections through its wall show it to be composed of 

 blood-clot, throughout which are scattered occasional villi 

 more or less completely dissociated. In some of them the 

 mesenchyme is fibrous. Some of the remnants of the villi 

 are surrounded by two zones of nuclei the remnants of 

 the two epithelial layers and lie in masses of leucocytes, 

 thus giving an appearance such as is frequently seen in 

 tubal pregnancy. 



(6) Severe infection. 



No. 929. 



(1) R. A. Hammack, Manila, Philippine Islands. 



(3) Patient aged 22 years. Two pregnancies, both end- 

 ing in abortion, this being the second. Normal period was 

 delayed about one month before abortion. No history of 

 infectious diseases. 



(4) The specimen consists of numerous small fragments 

 of blood, measuring together about 30 mm. in diameter, 



(5) Sections through a piece of what appears to be 

 chorionic tissue proved it to be a scrap of uterine mucous 

 membrane and a large clot of blood, a portion of which ia 

 fairly rich in leucocytes. A few very small fibrous villi 

 are found, and attached to them are very small, irregular 

 clumps of trophoblast. 



No. 941. 



(1) John Wade, Baltimore, Maryland. 



(2) A 30X20X10 mm. 



(4) The embryonic mass measures 60X40X20 mm., 

 and sections, as well as careful inspection, show it to be 

 composed mostly of decidua. On one side of it an ovum, 

 measuring 30X20X10 mm., was found, completely 

 filled with dense reticular magna, and a small vesicle 3 



