CHORION WITHOUT AMNION OR CYEMA. 



115 



do not stain with the Heidenhain method. The chorionic 

 wall and most of the villi are fibrous and locally thickened. 

 The latter are degenerate, surrounded by necrotic zones, 

 and anastomose freely. A strand of reflected mesen- 

 chyme bridges one end of the ccelom. A few buds of 

 syncytium protrude into the extensive mass of surrounding 

 blood. The entire specimen is encircled by considerable 

 fibrous substance, as well as by an outer, markedly in- 

 flammatory, and in part necrotic decidual zone. 

 (6) Marked infiltration. 



No. 750. 



(1) J. M. Jackson, Pittsburgh, Pennsylvania. 



(2) A 20X15X15 mm. 



(3) Patient aged 23 years; married March 25, 1913; 

 no previous pregnancies; last menstrual period June 6 

 to 10, 1913, and abortion August 19 following. First 

 intercourse two weeks after June 10 (Jewish law). Con- 

 ditions of uterus normal; no veneral diseases. Family 

 fertile. 



(4) The entire mass consists of a blood-clot, decidua, 

 and a large piece of an ovum, which together measure 

 45X30X25 mm. The ovum alone measures 20X15X15 

 mm., and is covered with numerous knob-like villi. 

 The main wall of chorion is very thin and transparent, 

 and when opened was found to be lined with a delicate 

 membrane. One half of the specimen is filled with an 

 extremely delicate reticular magma, and although the 

 inspection was made under favorable conditions, no trace 

 of an embryo was found. After the specimen was thor- 

 oughly examined, it became more and more doubtful 

 whether an amnion was present. 



(5) Sections later showed that it was absent. Small 

 fragments of decidua which were in the specimen were 

 decidedly fibrous. The chorionic membrane and villi 

 have undergone fibrous and mucoid degeneration. The 

 trophoblast is scanty, and there are a few buds of syncy- 

 tium, surrounded by a small amount of mucoid substance, 

 between the largely non-vascular villi. 



(6) Some hydatiform degeneration and probably chronic 

 endometritis. Decidua fibrous. 



No. 753. 



(1) L. A. Peek, West Palm Beach, Florida. 



(2) A 45X30X25 mm. 



(3) Patient 23 years old; married about a year; first 

 pregnancy. Usually about 32 days between menses. 

 First day of last period, May 19; abortion August 1 fol- 

 lowing. No infection of the uterus; no venereal diseases. 



(4) The specimen was found to consist of blood-clot 

 containing a cavity about 12 mm. in diameter, lined 

 with smooth membrane. No trace of embryo or amnion 

 could be found. 



(5) The sharply defined cavity of the ccelom is sur- 

 rounded by a thin, somewhat macerated chorionic mem- 

 brane. The magma is granular and contains disinte- 

 grating cells. In the fresh blood a few fibrous and mucoid 

 villi are contained. Outside there is a decidedly hemor- 

 rhagic and inflamed, partly necrotic decidua. In many 

 respects the chorionic wall resembles that of No. 752, 

 group 6. 



(6) Marked endometritis; lysis in decidua. 



No. 7656. 



(1) J. B. Harvie, Troy, New York. 



(2) A 55X35X20 mm. 



(3) Patient unmarried; one miscarriage 18 months be- 

 fore the present one. 



(4) The specimen, which was expelled spontaneously 

 while the patient was being etherized in the hospital, 

 measures 55X30X20 mm. and appears to be composed 

 of a collapsed, very hemorrhagic chorion. No trace of an 

 embryo could be found. 



(5) The cavity of the ovum, which is small (about 10 

 mm. in diameter), is infected, and the chorionic membrane 



is practically destroyed by a severe inflammation. The 

 villi, which are packed together, show mainly fibrous and 

 some mucoid degeneration. A great quantity of mucoid 

 substance is found between them. In this numerous buds 

 of syncytium and some small abscesses are contained. 

 The surrounding trophoblast and decidua are markedly 

 inflamed and the latter necrotic in several portions. 

 (6) Marked infiltration; hydatiform degeneration. 



No. 770. 



(1) C. S. Parker, Baltimore, Maryland. 



(2) A 12X9X6 mm. 



~. (3) Negro patient, aged 30 years, married 12 years, 

 bix births at terms and three or four abortions. Copula- 

 tion September 22. Menstrual period due September 28, 

 appeared September 30, lasting 9 days. Abortion Octo- 

 ber 5, probably induced. Vaginal discharges not foul- 

 smelling. No venereal diseases. Husband's family fertile. 



(4) Specimen consists of chorion with a few blood clots 

 attached. It is covered uniformly with villi, all of which 

 are equally developed. The ovum measures 12X9X6 

 mm. It was opened with great care and found to be well 

 filled with granular and reticular magma. The magma 

 was removed in a single mass, and on one side of the cho- 

 rion an irregular body about 2 mm. long was found. This 

 was at first thought to represent the embryo, but when 

 cut into serial sections was found not to be such. 



(5) The chorionic wall and villi are quite normal in 

 form and the trophoblast is plentiful. The specimen is 

 somewhat macerated, but it appears as though there is 

 some mucoid substance, in addition to the trophoblast, 

 between the villi. The nodular mass looks much like 

 an extension of mesenchyme into the crelom, with 

 strands of empty blood-vessels on either side of it. 

 There is an epithelial tube-like structure, which might 

 pass for the allantois or for the central nervous system. 

 Adjacent to this structure is an umbilical vesicle, the 

 blood-vessels of which communicate freely with those of 

 the chorion. 



(6) A normal, slightly macerated specimen. Decidua 

 not included. 



No. 791. 



(1) Ira L. Fetterhof, Baltimore, Maryland. 



(2) A 30X20X20 mm. 



(3) The specimen is said to be two months old. 



(4) The ovum, which measures 30X20X20 mm., is 

 entirely covered with villi about 4 mm. long, and from 

 one end arises a pedicle about 15 mm. long. The interior 

 is filled with a delicate reticular magma, and on one side 

 is an irregular body, 3 mm. long, which is adherent to 

 the chorion. 



(5) This small nodular mass is not well formed, and 

 appears to be largely disintegrated. Apparently it is 

 composed of two bodies, between which there is a clear 

 body, no doubt representing the yolk-sac. Sections of 

 the chorion show that the wall is somewhat thickened. 

 The villi are mostly mucoid and filled with a clear 

 mesenchyme without any blood-vessels. The tropho- 

 blast is composed mostly of small patches arising directly 

 from the surface of the villi, and at points it forms 

 rounded nodules, the centers of which are sometimes ne- 

 crotic. There is a small mass of mucoid substance between 

 the villi. 



(6) Hydatiform degeneration. Decidua absent. 



No. 829. 



(1) Austin Miller, Portersville, California. 



(2) A 38X38X30 mm. 



(3) Woman about 30 years of age, married 5 years. 

 Two previous pregnancies at term. Last menstruation 

 about November; abortion January 20. Uterus normal. 

 No venereal diseases. Family fertile. 



(4) This specimen consists of a white, shaggy ovum, 

 measuring 38X38X30 mm. About one-half of it is 

 devoid of villi, and in the denuded area a perfectly trans- 



