CHORION WITH AMNION. 



123 



but can still be outlined, and its interior is filled with 

 round cells. 



(6) Hydatiform degeneration. Decidua absent. 



No. 701. 



(1) George H. Hocking, Govans, Maryland. 



(2) A 70X50X30 mm. 



(3) Patient 22 years old. Married one year and the 

 mother of one child. Last period March 8; abortion 

 June 7, after a slight bloody discharge which had continued 

 for 2 weeks. 



(4) The chorionic mass, which measures 70X50X30 

 mm., contains a cavity 30X20 mm., lined by the 

 amnion, in which is a cylindrical mass 2 mm. in diameter 

 and 20 mm. long. No remnants of an embryo were found. 



(5) The specimen consists of a chorion with many well- 

 developed villi covered with a great quantity of necrotic 

 trophoblast, blood, and fibrin. In this irregular mass are 

 growing many buds of syncytium. The mesenchyme of 

 the villi is somewhat fibrous, and scattered through it are 

 many Hofbauer cells. Sections through the umbilical 

 cord show the remains of large blood-vessels, indicating 

 that the embryo was well developed shortly before the 

 time of the abortion. 



(6) Marked infiltration; early hydatiform degeneration. 



No. 7236 1 . 



(1) Lawrence L. Iseman, Chicago, Illinois. 



(2) A 60X40X40 mm. 



(4) Ovum filled with magma. Umbilical cord is normal 

 in appearance. 



(5) The structure of the villi and of the chorionic mem- 

 brane is quite normal. The mesenchyme of the villi 

 contains great quantities of Hofbauer cells, and is largely 

 non-vascular. Between the villi there is a great deal of 

 fresh blood, and into this are growing numerous buds of 

 syncytium. The surrounding tissue is markedly inflamed. 

 Remnants of the amnion are attached to one end of the 

 cord. 



(6) Marked infiltration. 



No. 72362. 



(1) L. L. Iseman, Chicago, Illinois. 



(2) A 50X35X30 mm. 



(4) Ovum with smooth, fleshy wall, which is thickened 

 and lined by the amnion, which has fused with the chorion. 



(5) The villi, which are necrotic, have undergone partial 

 mucoid degeneration and are surrounded by a degenerated, 

 fibrous decidua. The spaces between the villi are filled 

 entirely with fibroid which apparently has cut off the 

 nutrition. There is very little trophoblast. 



No. 757. 



(1) A. C. Smink, Baltimore, Maryland. 



(2) A 50X50X25 mm. 



(3) Patient aged 30 years; married in 1909. Two preg- 

 nancies. Last menstrual period June 20 to 24, 1913, and 

 abortion September 18 following. Condition of uterus 

 normal; no venereal diseases. Patient belongs to a prolific 

 familiy. 



(4) The specimen is disk-shaped and measures 

 50X50X25 mm. It is covered by a delicate membrane, 

 which suggests that the ovum has been turned inside out. 

 Sections of this mass show the interior to be composed 

 mostly of a stratified blood-clot, intermixed with numerous 

 irregular villi. 



(5) Microscopic examination shows that the outer 

 layer above noted is composed of the inverted membranes 

 which surround a blood-clot containing some villi. The 

 stroma of the latter is decidedly fibrous, non-vascular, and 

 degenerate, suggesting rapid destruction. The epithelium 

 is quite well preserved, but the "appendici durate" are 

 necrotic. Hofbauer cells are quite common, and the 

 stroma in many places, and even whole villi, have under- 

 gone coagulation necrosis. In other villi it is fenestrated. 



The blood-cells are well preserved in many portions of the 

 clot, but the stroma of both membranes has undergone 

 hyaline degeneration. 



(6) Decidua not included. 



No. 771a. 

 (1) B. T. Terry, Brooklyn, New York. 



(3) Patient had a miscarriage in 1900. From that time 

 until June 28, 1913, she menstruated regularly, then the 

 periods became irregular, until she was operated upon 

 September 5, 1913. At operation it was found that the 

 ovaries and left tube were normal, but that there was a 

 chronic endometritis. Venereal diseases denied. 



(4) The specimen is formed of blood-clot containing a 

 cavity 13 mm. in diameter. 



(5) The sections show very degenerate fibrous villi 

 which are matted together in hyaline material and necrotic 

 decidua. Between the villi and the decidua there is fibrin- 

 oid substance. The chorionic membrane is thickened, 

 macerated, and degenerated, and neither it nor the villi 

 contain any blood-vessels. The amnion, which is decidedly 

 macerated and degenerate, is folded. No evidence of 

 inflammation. 



No. 803. 



(1) W. J. Weese, Ontario, Oregon. 



(2) A 43X26X23 mm. 



(3) First pregnancy of a woman aged 21 years, married 

 March 23, 1913. Last menstrual period October 15 to 19, 

 1913, and abortion November 26 following. No infection 

 of uterus. No venereal diseases. Mother of patient had 

 one abortion. 



(4) The chorion has a very thin, hemorrhagic wall lined 

 with a smooth membrane. On one end is a small tuft of 

 villi. There is a considerable reticular magma, and on one 

 side a nodular embryo 3 mm. long. 



(5) The chorionic membrane, which is somewhat fibrous, 

 is covered with matted villi which have undergone fibrous 

 degeneration. There is a great deal of fibrinoid and large 

 hemorrhages. On the outside is a layer of unorganized 

 clot. The nodule consists of what appears to be a collapsed 

 amnion. As the sections were not serial, it is impossible 

 to determine the exact relation of this membrane to the 

 ehorion. The decidua is decidedly necrotic, fibrous, 

 slightly infiltrated, and hemorrhagic. 



(6) Slight infiltration. 



No. 813. 



(1) H. D. Taylor, Baltimore, Maryland. 



(2) A 80X50"X25 mm. 



(3) First pregnancy of a woman aged 24 years, married 

 August 10. Last menstrual period June 13 to 17, same 

 year; abortion December 30 following. No venereal dis- 

 eases. Family fertile. 



(4) The specimen appears ulcerated and is composed of 

 a flattened oval mass measuring SOX SOX 25 mm. After 

 opening it, the chorionic wall was found to be sharply 

 defined, with numerous hemorrhages between the villi. 

 The cavity measures 70X35 mm. and is filled with a tough, 

 clear jelly. 



(5) Sections of the chorion show that the wall is very 

 thick and fibrous, and that at many points it appears to be 

 composed of two layers. The amnion is closely attached 

 to the chorion. Some of the villi are completely degen- 

 erated, and others are fibrous and matted together by a 

 large amount of fibrinoid substance. There is a neerotic 

 decidua, the cells of which are arranged in whorls in some 

 places, and which is markedly infiltrated in some areas. 



(6) Marked infiltration. 



No. 814. 



(1) J. M. Melton, Crozet, Virginia. 



(2) A 55X25X25 mm. 



(3) The sixth pregnancy of a woman aged 43 years, mar- 

 ried 18 years. Fourth pregnancy ended in abortion 7 



