CYLINDRICAL CYEMATA. 



143 



latter and the chorionic wall are small irregular villi, most 

 of which are degenerated, and which contain a scanty 

 amount of trophoblast. The stroma of the yilli, which is 

 somewhat hyaline and partly mucoid, is rich in nuclei. 

 The chorionic wall appears to have undergone a gradual 

 atrophy. The embryo is greatly dissociated. The central 

 nervous system is practically solid, and attached to the 

 brain in front are small atrophic, but completely disso- 

 ciated, eye-vesicles. One of these shows a small amount 

 of pigment formation. The spinal cord contains a lumen 

 throughout the greater length of the body. The heart and 

 blood-vessels are easily outlined by the blood within them, 

 but their walls are indistinct. A slight indication of ccelom 

 where it passes into the umbilical cord, and a remnant of 

 the intestines can be made out. The cord has undergone 

 maceration and the extremities are atrophic. 

 (6) Decidua slightly infiltrated. 



No. 621. 



(1) George H. Hocking, Govans, Maryland. 



(2) A 70X45X40 mm.; B 3mm. 



(4) The specimen is pear-shaped, dark, and well cov- 

 ered with deeidua. The walls are thick, measuring at 

 points over 10 mm. Within is a cavity 20X20X20 mm., 

 filled with clear fluid, in which floats a transparent vesicle. 

 The amnion is suspended in the ccelom, which is lined with 

 most delicate and transparent retieular magma. On one 

 side is an atrophic embryo 3 mm. long. 



(5) The chorionic wall is transparent, but may be a 

 little more fibrous than in normal specimens. The villi 

 also are somewhat fibrous and non-vascular, with consid- 

 erable trophoblast attached to them. This in turn has a 

 fairly normal connection with the deeidua. The latter is 

 somewhat fibrous and hemorrhagic, with very little leu- 

 cocytic infiltration. The intervillous spaces contain some 

 blood and considerable stringy matter, the latter being 

 filled with buds of syncytium. At certain points there are 

 very large spheres of trophoblast; in some places the tips 

 of the villi end in them, and others pass through them. 

 The embryo is markedly dissociated and is partly filled 

 with round cells. In the head the central nervous system 

 is distended, although the outline is still preserved. The 

 eye-vesicles are very atrophic, and the brain reaches only 

 to the upper part of the body. In this region the heart, 

 which lies within a well-formed pericardial cavity, begins. 

 From it arise two vessels which run down to the point of 

 attachment of the embryo to the thickened amnion, which 

 divides near this point, forming a very large vesicle noticed 

 in the specimen before it was cut. One side of this is closely 

 attached to and directly continuous with the chorion. 

 In the lower part of the embryo there is a row of cells 

 running along the dorsal side, probably the dissociated 

 cord. The ccelom is well formed. 



No. 639. 



(1) Edwin B. Fenby, Baltimore, Maryland. 



(2) A 18X12X12 mm.; B 6mm. 



(3) Patient took 8 grains of quinine to break up a cold 

 and two or three days later had an incomplete miscarriage. 

 She did not think she could have been pregnant more than 

 two weeks, and said she did not know she was in that 

 state. The specimen was obtained through curettage for 

 an incomplete miscarriage. 



(4) The ovum is covered with irregular patches of 

 ragged villi and filled with a dense mass of granular magma. 

 Within there is a disintegrated embryo whose greatest 

 length is 6 mm. There are also two round bodies, about 

 1 mm. each in diameter, which probably are the arms. 



(5) The chorionic wall and villi are somewhat fibrous, 

 with practically no trophoblast. Sprouts of syncjtium 

 arise from some of the villi. The embryo is badly macer- 

 ated, and the brain is completely dissociated, there being 

 no lumen present. The boundaries of the spinal cord are 

 indistinct. Only a portion of the embryo was cut into 

 serial sections. 



No. 655. 



(1) A. G. Singewald, Baltimore, Man land 



(2) A 30X30X10 mm.; B 4mm. 



(3) White patient, aged 36 years; married 18 years 

 Has had nine pregnancies four abortions and five births 

 at term Four children living. Three abortions occurred 

 within the last three jears. The first two took place in an 

 interval between full-term births. All were induced 

 Ihe patient last menstruated January 22 to 27 and the 

 abortion occurred March 21, having been induced Feb- 

 ruary 28 Bleeding from the uterus began March 1 and 

 continued intermittently until March 21. Uterus rather 

 enlarged Part of placenta retained. No infection- no 

 venereal diseases. 



(4) The ovum was carefully examined, and a fine retic- 

 ular magma was found lying so closely about the embryo 

 yolk-sac, and belly-stalk that great care was necessary to 

 obtain a clear view of it without the retieular fibers pulling 

 on the amnion or yolk-sac. The embryo appeared to bl 

 normal, with normal amnion; the yolk-stalk lay to the 

 left the belly-stalk to the right; the ccelom is wide open 

 posteriorly. The heart and lungs are most prominent 

 In general it might be said that the body below the heart 

 is unusually short, but it may be flexed. Direct measure- 

 ment of the embrjo through the amnion while in alcohol 

 gave 4 mm. as the greatest length. The edges of the 

 ovum opposite the embryo are denuded for a few milli- 

 meters, but the remainder is covered closely with villi 

 which reach 5 mm. in length and branch two or three times! 



(5) The sections of the chorion show that the villi are 

 normal in form, but macerated. All of them contain 

 blood-vessels and blood. There is considerable tropho- 

 blast and a peculiar mucoid substance between the villi 

 The embryo appears to be normal in form, but badly 

 macerated, but whether it is dissociated is impossible to 

 determine. Judging from the history, it was probably 

 killed some time before the abortion. 



(6) Decidua absent. 



No. 669. 



(1) O. S. Lowslej, New York. 



(2) B 7mm. 



(3) Patient's last period two months before abortion. 



(4) The club-shaped embryo was attached to a small 

 piece of fibrous chorion, on which there were no villi. 



(5) The dissociated brain almost completely fills the 

 head of the embryo, and the tissues of the body have under- 

 gone extreme dissociation. It is difficult to outline any 

 other organs, although there are indications of the verte- 

 bra and spinal nerves. In place of the heart there is a 

 large group of round cells, but these grade over into the 

 adjacent tissues. 



No. 690. 



(1) D. V. Adnaine, Williamstown, Massachusetts. 



(2) A 40X35X25 mm.; B 7mm. 



(3) The specimen came from a woman 36 years of age, 

 who has been married 7 years. She is the mother of a 

 child 6 years old, and had an abortion August 15, 1910. 

 Last menstrual period October 20, 1911; abortion Jan- 

 uary 12 following. 



(4) The ovum measures 40X35X25 mm. One half 

 of it is covered with well-developed villi; the other half is 

 fibrous, with but few ragged villi. The interior is filled 

 with a clear fluid. Within the amniotic cavity is an atro- 

 phic embryo 7 mm. long, without any well-defined umbil- 

 ical cord. From the front the organs are protruding, and 

 in front of the head is a small, club-shaped nodule, which 

 it was thought may represent the heart. 



(5) A portion of the ovum was cut into serial sections 

 to get the relation of the membrane, and the embryo was 

 cut sagittally. The sections give its greatest length as 

 7 mm. Sections of the chorion and villi show that the 

 mesenchyme is edematous and contains but very few 

 blood-vessels. The trophoblast is scanty, but at points is 



