STUNTED CYEMATA. 



151 



trunk of an embryo attached to the chorion by a thin 

 cord. On the opposite side of the ovum the head is located, 

 also embedded in magma. Over the body of the embryo 

 there is a greenish-colored nodule 4 mm. in diameter, 

 which proves to be the degenerated umbilical vesicle. 

 The legs are poorly formed and stubby. 



(5) Sections of the chorion show that the mesoderm of 

 the villi is hyaline, and therein remnants of blood-vessels 

 may be seen; a normal number of round nuclei are scattered 

 through it. The trophoblast also appears to be normal. 

 Between the villi may be seen some mucus containing 

 leucocj tes. No decidua is attached to the villi. The cord 

 is thin at its attachment to the chorion, and is slightly 

 enlarged midway between the chorion and the embryo. 

 Here it contains large mesodermal spaces, which at points 

 are infiltrated with round cells. The umbilical vesicle 

 is present only in outline and its lumen is partly filled 

 with debris. However, some beautiful multipolar meso- 

 derm cells may be seen. The epidermis covers the embryo 

 only in part; a shell of granular magma covers the rest 

 of the body. The tissues are greatly dissociated and 

 macerated, which has caused almost complete oblitera- 

 tion of the outlines of the epithelial lining of the alimentary 

 canal. The central nervous system is nearly solid, and 

 the large blood-vessels are gorged with blood. The liver 

 is necrotic. The mesodermal tissues are obscured, 

 with the exception of the cartilages, whose outlines are 

 sharpened. 



(6) Hjdatiform degeneration. Decidua absent. 



Nos. 330 a, b. 



(1) J. Park West, Bellaire, Ohio. 



.,. , . / (a) A 60X55X50 mm.; B 12mm. 



(} rwins^ (6) A 55x50x45 mm.; B 12mm. 



(3) "The woman from whom these twin specimens 

 were obtained is about 25 years of age. Fifteen months' 

 ago she gave birth to an 8 months child which lived for 2 

 days. Her last regular menstrual period took place 

 during the middle of September. The October and 

 November periods were missed. About the middle of 

 December, at her regular time, bleeding began, which 

 continued until January 21, when these two ova were 

 aborted. I am quite positive, but not certain, that the 

 woman has syphilis." 



(4) Both ova have smooth surfaces, being composed of 

 thin walls, upon which there are occasional villi. 



(5) In both specimens the villi are irregular, fibrous, 

 non-vascular, and embedded in a mass of pus, in which 

 may be found much necrotic syncytium, fibrin, and blood. 

 Many leucocytes are found in the mesoderm of the villi. 

 The chorion and amnion of both specimens are of irregu- 

 lar thickness and well blended with each other. The 

 changes in the two embryos are very similar. In both the 

 epidermis is intact and the dermis thickened. In front 

 of the head, in the region of the deformed mouth, there 

 are peculiar thickenings of the epidermis. Both spinal 

 cords are markedly dissociated. The dissociation of the 

 brains is so extensive that the cerebral vesicles and mid- 

 brains are nearly destroyed, and the hind-brains occupy 

 spaces in the centers of the deformed heads. The large 

 vessels and heart are gorged with blood. In 3306 the wall 

 of the ventricle is well infiltrated, and in 330<z nearly 

 destroyed by the migrating cells. The outlines of the 

 organs and tissues are very obscure, the whole being more 

 or less filled with round cells. Some of the liver tissue is 

 necrotic. 



(6) Decidua necrotic and infiltrated; chorionic changes 

 suggestive of lues. 



No. 334. 



(1) B. J. Merrill, Stillwater, Minnesota. 



(2) A 50X40X30 mm.; B 5 mm. 



(3) " Last period 4 weeks before. About 10 days before 

 abortion there was some bleeding, which repeated itself 

 at intervals, and was finally followed by the abortion." 



(4) Examination of the mass proves that it is made up 

 mostly of uterine mucous membrane, decidua, and blood, 

 and that it contains a cavity 15 mm. in diameter. 



(5) The chorion can still be made out as a very macer- 

 ated, fibrous band. The amnion is almost completely de- 

 generated, the villi are macerated, the non-vascular stroma 

 :lear and wavy, but the epithelium and trophoblast 

 ;airly well preserved. 



(6) Decidua and mucosa infiltrated; hydatiform de- 

 generation. 



No. 336. 



(1) J. Park West, Bellaire, Ohio. 



(2) A 35X25X15 mm.; B 8 mm. 



(4) The ovum is smooth, one end being covered with 

 well-developed villi. 



(5) Their mesoderm is hyaline, with scattered nuclei 

 containing some remains of blood-vessels. The main wall 

 of the chorion is fibrous and infiltrated with blood-cells 

 from the embryo. Within, there is a cavity (15X10mm.) 

 filled with granular magma and containing the umbilical 

 vesicle and the embryo, which is closely encircled by the 

 amnion. The embryo is somewhat distorted, with large 

 blood-vessels filled with blood and tissues infiltrated with 

 round cells. What is especially noteworthy is that the 

 circulation within the chorion has been cut off, the cord 

 being atrophic and infiltrated. The large omphalo- 

 mesenteric vessels are filled with blood and spread over 

 the yolk-sac, the walls of which are necrotic. 



(6) Decidua absent. Hydatiform degeneration. 



No. 339. 



(1) C. S. Minot, Boston, Massachusetts. 



(2) A 50X30X30 mm.; B 16 mm. 



(4) The chorion is thin, covered by only a few villi and 

 hemorrhagic at one end. 



(5) In structure it is somewhat hyaline at points and 

 at others somewhat fibrous. The villi are largely non- 

 vascular, fibrous, and hyaline. The cord is thickened and 

 fibrous. The walls of its blood-vessels are dissociated, and 

 the blood from them is infiltrating the surrounding tissues. 

 The embryo is somewhat distorted, but normal in form. 

 Within, the tissues are dissociated and macerated. The 

 large blood-vessels are distended with blood, and within 

 the liver and heart the blood-cells from them have ex- 

 tended into the surrounding tissues. 



(6) Decidua absent. 



Nos. 341 a, b. 



(1) C. S. Minot, Boston, Massachusetts. 



(2) A 70X60X50 mm.; B 14 mm. 



(4) The ovum is pear-shaped and smooth, being covered 

 with some decidua and at points with hemorrhagic masses. 

 Its tissue does not stain well, but some of the villi appear 

 to be fibrous and others edematous. There is not much 

 syncytium present. Possibly there are masses of leu- 

 cocytes in the decidua. Within the ovum are two stumpy 

 embryos, both of which have dilated cords which come to a 

 point where they are attached to the chorion. 



(5) These dilatations show the usual mucoid changes 

 with cavity formation. The embryos are dissociated and 

 macerated. The large blood-vessels are filled with blood, 

 and it appears as if the migrating cells had infiltrated 

 much of the tissues. 



(6) Decidua too necrotic; probably some hydatiform 

 degeneration. 



No. 343. 



(1) C. S. Minot, Boston, Massachusetts. 



(2) A 55X45X35 mm.; B 11 mm. 



(4) The chorion is mostly smooth and of unequal 

 thickness. The decidua is necrotic and infiltrated with 

 numerous leucocytes. Below it there are distorted villi 

 with fibrous, non-vascular mesoderm. The amnion is in 

 contact with the chorion. Between the villi there is a 

 tringy mucoid mass rich in leucocytes. The stumpy 



