OCCURRENCE OF LOCALIZED ANOMALIES. 



197 



obtained from the uterus, while slightly more than 8 per cent were ectopic. The 

 comparative frequency of pathological and normal embryos can be ascertained, 

 however, by comparing them within a given century, or for the whole 1,000 to- 

 gether. In the uterine specimens about one-third of the ova and embryos are 

 pathological, as compared to two-thirds in the ectopic. In other words, patho- 

 logical specimens are twice as frequent in ectopic as in uterine pregnancy. 



Table 10 includes all the specimens in which there are pronounced localized 

 anomalies. The character of the anomaly for the individual specimens recorded 

 is given in tables 11 and 12. From these tables it would appear that there are 

 about as many anomalies among the normal as among the pathological specimens, 

 but when these figures are compared with the total number of specimens, both 

 normal and pathological, it becomes evident that localized anomalies occur about 

 twice as frequently in the pathological as in the normal embryo. Thus, 38 out of 



TABLE 10. Distribution of specimens with localized anomalies (to be compared with table 7). 



396 pathological specimens, or about 10 per cent, exhibit localized anomalies, as 

 against 6 per cent in 604 normal specimens. The 38 pathological specimens with 

 localized anomalies listed in table 10 were aborted in the early part of pregnancy, 

 and only one of them (No. 649) grew to a sitting height of 90 mm., that is, to 

 about the middle of the fourth month. 



The number of normal embryos with localized anomalies tends to decrease 

 before the fifth month, there being but 1 in the sixth, 1 in the eighth, and 4 in the 

 tenth month, the end of pregnancy. In other words, all pathological specimens, 

 either with or without localized anomalies, are aborted in the first half of pregnancy, 

 as are also nearly all so-called normal embryos with slight malformations, very 

 few of them reaching full term. 



We have made an especial effort to collect specimens of full-term monsters 

 as well as abortion material from all months of pregnancy. Only the first 100 

 specimens of the collection show an unusually large percentage of normal embryos. 

 Although at first an effort was made to collect only good, normal specimens, the 

 last 900, including all sorts of material, carry about the same percentage of 

 normal specimens throughout. Among the first 1,000 specimens of our collection 

 there are not many fetuses from the second half of pregnancy, but we are now 



