Oxygen Consumption. 187 



It is somewhat in the field of speculation to suggest the possibilities of the use 

 of the direct measurement of oxygen for studying metabolism, but certainly, 

 inasmuch as it renders possible a reasonably accurate study of the role that 

 glycogen plays in katabolism, it has already proved of incalculable value in indi- 

 cating to what extent diabetics can draw upon their already meager supply of 

 glycogen. It is not out of the bounds of probabilities to state that the direct 

 determination of oxygen in experiments of a pathological nature may throw an 

 entirely new light upon the significance of the storage of glycogen in the body, 

 the quantity of glycogen, and the rapidity with which this glycogen can be 

 drawn upon to make up drafts upon body-material. Particularly is this the case 

 in subjects where the storage of body glycogen is very low, as in diabetics. 



