I'.UG.] NATURAL SCIENCES OF PHILADELPHIA. 'i 



1 Mi Hi hours Hermann's fluid Moderate meal. 



147 'J 1 hours Hermann's fluid Moderate meal. 



IIS IShours Hermann's fluid Moderate meal. 



! I!) 24 hours Hermann's fluid Moderate meal. 



!.">() 24 hours Hermann's fluid Moderate meal. 



152 18 hours. Hermann's fluid. 



153 24hours Hermann's fluid Heavy meal. 



1.">I 24 hours. 



175 12'. hours Hermann's flui 



17(1 i:».l hours Hermann's fluid. 



177 14 -J- hours Hermann's fluid. 



178 I."), 1 , hours Hermann's fluid. 



179 16| hours Hermann's fluid/ 



180 17'. hours Hermann's fluid. 



lsi ISA hours Hermann's fluid. 



182 IShours Hermann's fluid. 



246 1 hour A. C. A Lightmeal. 



247 4 hours r..A. C. A Heavy meal. 



'_MS 2 hours A. C. A Moderate meal. 



•_'|o 3hours A. C. A Moderate meal. 



'-'.">(> ."> hours. A. C. A Heavymeal. 



•_'.")1 1 * hours A. C. A Very light meal. 



252 2\ hours A. C. A Very light meal. 



253 6hours A. C. A Heavy meal. 



•_'.")7 3 hours Hermann's fluid Moderate meal. 



258 4 hours A. C. A Moderate meal. 



261. 4 hours Hermann's fluid Heavymeal. 



262 5 hours Hermann's fluid Moderate meal. 



Prior to taking up the description of the findings in the cells, it is 

 desirable to call attention to a phenomenon first signalized by Erd- 

 mann (1910). This is the exfoliation of the intestinal epithelium 

 which appears to follow ingestion of the spores of Sarcocystis. The 

 natural inference would be that this was due to the invasion and 

 subsequent destruction of the cells by the parasites, and such was 

 my original idea (Crawley, 1913). No doubt a certain amount of 

 exfoliation is to be accounted for in this way, but other factors are 

 involved. Thus Erdmann found that the ingestion of an extract of 

 Sarcocystis cysts, from which the spores themselves had been removed, 

 was followed by exfoliation, and data that I shall now give show 

 that the exfoliation takes place before any extensive invasion of the 

 cells. 



The intestines of a series of mice, all of which had been killed 

 within 6 hours after feeding, were examined and the conditions 

 presented by the epithelium in various parts of the intestine noted. 

 The results of this examination are tabulated below. Where no 

 exfoliation was demonstrable, the condition is indicated by the word 

 "none." Where, however, it is in evidence it is designated as 

 •-lie lit," "moderate," or "severe," according to its degree. 



