30 PSYCHOLOGICAL EFFECTS OF ALCOHOL. 



a ''moderate dose" is determined neither by general experimental 

 agreement nor by convention. Single experimental doses vary in the 

 literature from 10 c.c. to 100 c.c. and over. Almost any size of dose 

 would have precedents enough. Meyer and Gottlieb 1 place the " stimu- 

 lating" dose for abstemious adults at 30 to 40 grams, adding that for 

 those accustomed to its use the dose must be larger. As a standard 

 dose we adopted what seemed to be a fair average of 30 c.c. (actually 

 29.8 c.c.). In the text we refer to this standard dose as dose A.~ 



Two variations of the standard dose were made for methodological 

 reasons. In the 12-hour experiments, 12 c.c. was given hourly for 8 

 consecutive hours, excepting the hour of lunch. This is called in the 

 text dose C. A dose of 45 c.c. (actually 44.7 c.c.) was given to the 

 regular group of moderate drinkers on a sufficient number of experi- 

 mental days to obtain adequate measurements in Series I A, HA, and V. 

 We refer to this dose in the text as dose B. 



In order to relieve somewhat the disagreeable raw taste of the 

 diluted alcohol, one-third of the total volume consisted of a solution 

 of cereal "coffee." 3 Fruit juices, which we tried, proved to be dis- 

 agreeable to one of the first subjects and were consequently abandoned. 

 The liquids were invariably drunk at room temperature, about 20 C. 

 The total volume of dose A was 150 c.c.; that of dose B was 225 c.c. 

 In all cases the alcohol and control mixtures were administered by 

 mouth, the subjects being instructed to drink the mixtures as rapidly 

 as convenient. 



GENERAL ARRANGEMENT OF THE APPARATUS. 



The research occupied a specially constructed laboratory of the 

 Nutrition Laboratory, measuring about 5.5 by 3.5 meters, with a 

 balcony about 4.5 by 3.5 meters. All the experimental records were 

 made in this room. The incidental photographic work, such as 

 loading the plate and paper holders, and developing the photographic 

 records, was done in a small dark-room which was partitioned off in one 

 corner of this laboratory. 



Uniform lighting of the room during experimental sessions was 

 insured by shutting out the variable daylight altogether, and by the 

 use of incandescent electric lights. Ventilation was provided for by 

 forced draught. An electric fan to provide free circulation of air in 



and Gottlieb, Experimentelle Pharmakologie, Berlin, 1914. 



2 In the original preparation of the standard solution of pure grain alcohol to be used in this 

 research, emphasis was laid upon the constancy of the amount in each dose rather than the 

 absolute values. Owing to a misstatement on my part, Professor Dodge used the values 25 c.c. 

 and 37.5 c.c. as representing the amount of absolute alcohol in the two doses employed in thia 

 research in giving preliminary reports of the work at the 1914 meeting of Experimental Psychol- 

 ogists at Columbia University, and at the Philadelphia meeting of the American Psychological 

 Association in 1915. The true values should have been 30 c.c. and 15 c.c., respectively. The 

 error is wholly mine. F. G. B. 



'Prepared from roasted cereal and obviously free from caffein. 



