PULSE DURING MENTAL AND PHYSICAL WORK. 



187 



Alcohol was found to increase -pulse-rate by: 



Parkes and Wallowicz, 1 INTO. Man; 

 moderately large doses. 



Dogiel 2 (ref.).* First ri.sc, then fall; no 

 data cited. 



Fraser, 3 1880. Man; 75 c.c., 20 per cent. 



v. Jaksch, 4 1888. Children, 2 to 3 g. 



Binz, 5 1888. Dog; 5 c.c.; stomach. 



Swientochowski, 6 1902. Patients; 25 to 100 

 c.c. ; 50 per cent. 



Mosso and Galeotti, 7 1903. Men; mod- 

 erate. 



John, 8 1909. Men; moderate. 



Alcohol was found to hare no effect on pulse- 

 rate by: 

 Zimmerberg 13 (ref.), 1869. Various animals 



60 c.c. ; Man, 40 per cent Al. 

 Von der Muhll and Jaquet, 14 1891. Men, 



30 to 100 c.c. 

 Bock, 15 1898. Isolated rabbit heart, 255 



c.c. ; 10 per cent. 

 Wendelstadt, 16 1899. Men, irregular, 5 to 



100 c.c. (actually rose two-thirds cases). 

 Rosenfeld, i; 1901. Dogs, 2 to 29 c.c, A. A. 

 Kochmann, 18 1904-5. Man; moderate, 60 



to 80 c.c., 20 per cent; 50 c.c., .30 per cent. 

 Wood and Hoyt, 19 1905. Dogs; various, 



moderate, irregular. 

 Bachem, 20 1907. Rabbits; 0.2 to 1.0 c.c. 

 Dixon, 21 1907. Man; moderate; dilute. 

 Deunig et a/., 22 1909. Fever patients; 



6 to 40 c.c. 

 Woodhead, 23 1911. Man; moderate. 



Alcohol was found to decrease pulse-rate by: 



v. Jaksch, 4 1888. Children, 3.2 gr. ; 



patients, 75 per cent of cases. 

 Gutnikow, 9 1892. Dog; 100 to 250 gr.; 



50 to 70 per cent. 

 Hascovec, 10 1900-01. Dog; 5 c.c. A. A., 



25 per cent intravenous; 20 c.c. A. A., 



33 per cent; 100 c.c. A. A., 50 per cent. 



stomach. 

 Backmann, 11 1906. Isolated rabbit heart, 



0.05 to 0.5 per cent. 

 Di Cristina and Pentimalli, 12 1910 (ref.). 



All doses. 



Alcohol 



ami 



was found both to increase 

 decrease pulKe-rale by: 



Maki 24 (ref.), 1884. Frog; small doses. 

 Weissenfeld. 25 Self; 50 to 70 c.c. sherry; 



irregular. 



Loeb, 26 1905. Frog and cat; inconstant. 

 Dixon, 21 1907. Frog; first slow, then rapid. 

 Brandini, 27 1908. Rabbit and dog; depres- 

 sion moderate; isolated heart. 

 Luzzato, 2 * 1910-11. Men (ref.); 20 to 



50 c.c. Al.; individual differences. 

 Miller, 29 1910. Animal; transfused; 0.13 



to 0.3 per cent stimulated; over 0.3 



per cent depressed. 

 Downs, 30 1911. Frog; external application 



to heart; 1 to 2 per cent increased at 



first; 5 per cent decreased. 



*Original not available. 



Parkes and Wallowicz, Proc. Royal Soc. of London, 1870, 18, p. 362; Parkes, Proc. Royal 



Soc. of London, 1874, 22, p. 172. 

 2 Dogiel, Fourth Congress of Russian Naturalists in Kasan, reported in Archiv f. d. ges. Physiol., 



1874, 8, p. 604. 



3 Fraser, Alcohol, its function and place, Edinburgh, 1880. (Ref.) 

 V. Jaksch, Verhdl. des Congresses fur innere Medizin, Wiesbaden, 1888, 7, p. 86. 

 'Binz, Verhdl. des Congresses fur innere Medizin, Wiesbaden, 1888, 7, p. 70. 

 "Swientochowski, Zeitschr. f. klin. Med., 1902, 46, p. 284. 

 ''Mosso and Galeotti, Lab. Sci. Int. du Mont Rosa, 1903. (Published 1904.) 

 "John, Zeitschr. f. exp. Path. u. Then, 1909, 5, p. 579. 

 Gutnikow, Zeitschr. f. klin. Med., 1892, 21, p. 168. 

 '"Hascovec, Mitteilungen der bohmischen Akademie, 1900-01. 

 ^Backmann, Skand. Archiv f. Physiol., 1906, 18, p. 323. 

 12 Di Cristina and Pentimalli, Archiv di Fisiol., 1910, 8, p. 131. 

 13 Zimmerberg, Dissertation, Dorpat, 1869. (Ref.) 



14 Von der Muhll and Jaquet, Corresp.-Blatt f. schweizer Aerzte, 1891, 21, p. 457. 

 l6 Bock, Archiv f. exp. Path. u. Pharm., 1898, 41, p. 158. 

 'Wendelstadt, Archiv f. d. ges. Physiol., 1899, 76, p. 223. 



"Rosenfeld, Der Einfluss des Alkohols auf den Organismus, Wiesbaden, 1901. 

 18 Kochmaun, Archiv. internat. de Pharmacod. et Therapie, 1904, 13, p. 329: Deutsch. Med. 



Wchnsch., Leipsic, 1905, 31, p. 942. 



"Wood and Hoyt, Mem. Nat. Acad. Sciences (pub. 1905), 1911, 10, p. 39. 

 20 Bachem, Zentralbl. f. innere Med., 1907, 28, p. 849. 

 '"Dixon, Journ. Physiol., 1907, 35, p. 346. 



^Dennig et al., Deutsch. Archiv f. klin. Med., 1909, 96, p. 153. 

 ^Woodhead, Med. Press and Circ. London, N. S., 1911, 92, p. 553. 

 M Maki, Ueber den Einfluss des Camphers, Caffeins und Alkohols auf das Herz. Dissertation, 



Strassburg, 18S4 (cit). 



M Weissenfeld, Archiv f. d. ges. Physiol., 1898, 71, p. 60. 

 26 Loeb, Archiv f. exp. Path. u. Pharm., 1905, 52, p. 459. 

 "Brandini, Archiv. Ital. de Biol., 1908, 49, p. 275. 

 28 Luzzato, Archiv. Ital. de Biol., 1910, 54, p. 291. 

 "Miller, Journ. Am. Med. Asso., 1910, 55, p. 2034. 

 "Downs, Month. Cycl. and M. Bull., 1911, 4, p. 153. 



