268 PSYCHOLOGICAL EFFECTS OF ALCOHOL. 



II. Alcohol doses continued. 



4. When administered continued. 



b. With food continued. 



3. With carbohydrates. 



4. With condiments. 



5. With glucose or nutritive enemata. 



6. After or with a very hearty meal, i. e., when stimulated by large amounts 



of protein, and by large amounts of food with little protein or little 

 stimulation. 



c. During fatigue. 



1. Mental fatigue. 



2. Physical fatigue. 



d. During sleep (wake up from sound sleep and take dose and sleep afterwards). 



III. Absorption of alcohol : 



1. Absorption rate. 



a. From stomach. After introduction into stomach, use stomach pump. (Lavage. ) 



b. From colon. After enemata, irrigate, determining alcohol in residue after vary- 



ing lengths of time. 



c. By digestive tract vs. by respiratory tract. Which is quicker? Results to be 



noted by respiratory exchange. (Leonard Hill.) 



2. Completeness of absorption to be ascertained. 

 No alcohol in urine, feces, etc.? 



3. Absolution by skin to be tested. 



IV. Circulation: 



1. Heart-beat and pulse. 



a. Graphic tracings by sphygmograph. 

 Radial artery. 

 Carotid artery. 

 Capillary plethysmograph. 

 Electro-cardiograms. 



Studying changes in the character and in rate of propagation of pulse-waves. 

 Effect of irritation of the stomach on the heart-beat. 

 5. Pulse-rate. 



(1) Resting subject, michtern, lying quietly until pulse has reached minimum 



level before alcohol is administered, 

 (a) Use minute pulse as unit. 

 (6) Use pulse in two respiratory rhythms as a unit (electro-cardiogram). 



(2) During sleep, if possible. 



(3) During muscular work. 



(a) Riding a bicycle ergometer at definite rate of revolution and degree of 

 resistance. Ride till pulse constant, then take alcohol while riding. 



(6) Is maximum pulse level affected by alcohol taken just prior to muscular 

 work? Time to reach same or actual level. 



(c) Is time of return to minimum pulse lying down after work altered? Is 

 actual level after work altered? 



(4) During various forms of mental activity. 



2. Vasornotor reactions. 



a. Plethysmograph observations. 



b. Blood-pressure. 



(1) Resting. 



(2) Severe muscular work. 



Quasi-continuous records (Erlanger sphygmomanometer) . After rectal 

 administration . 



c. Note alteration in cutaneous circulation. 



Is parallelism noted in temperature curves from rectum, groin, axilla affected? 

 (Also skin temperature curve if possible.) (See Body temperature.) 



d. Effect of alcohol on splanchnic circulation. Rapidity of stomach and intestinal 



movements. (See Digestion.) 



3. Rate of blood flow (Krogh.) 



