INGESTION OF FAT. 



257 



seem to confirm Gigon's 1 contention that the ingestion of a fat diet may 

 result in a decreased katabolism. On the other hand, as the carbon- 

 dioxide production and oxygen consumption showed a positive, though 

 slight, increase and Gigon's measurements were based upon the gaseous 

 metabolism and not upon direct measurements of the heat production, 

 it is evident our observations can give no support to Gigon's theory. 

 D. J. M., March 23, June 3, and June 7, 1910. In this series of 

 3 experiments, 221 grams, 398 grams, and 376 grams of cream, re- 

 spectively, were taken. The subject was not especially satisfactory, 

 as he was inclined to be restless; it is particularly unfortunate, there- 

 fore, that he should have been selected for this study in which so slight 

 an effect upon the metabolism would be produced as with cream. 

 Hence the three experiments can be treated only in a general way and 

 discussion of the individual periods is unjustifiable. The results of 

 the experiments are given in tables 188, 189, and 190. From an exam- 

 ination of the data it is seen that there was no positive increase in any 

 of the factors measured in the experiment of March 23. In the experi- 

 ment on June 3 there was a total increment of about 4 grams in carbon- 

 dioxide production, 11 grams in oxygen consumption, and 20 calories 

 in heat production. Similar increases in the first two factors are seen 

 in the experiment of June 7, but not in heat production. The detailed 

 pulse records (not given in the tables) show very little increase in the 

 experiment of March 23, but in the experiment of June 3 there was a 

 change from an average of 63 in the preliminary period to an average 

 of 69 after food. A similar change in the pulse rate occurred in the 

 experiment of June 7. 



TABLE 188. D. /. M., March 23, 1910. Sitting. (1-hour periods.) 



Cream: 



Amount, 221 grams; nitrogen, 0.85 gram; total energy, 673 cals. 



Fuel value: Total, 666 cals.; from protein, 3 p. ct.; from fat, 91 p. ct.; from carbohydrates, 

 6 p. ct. 



Nitrogen in urine, 0.40 gram per hour. 2 

 Basal values (March 23, 1910): CO 2 , 25.5 grams; O 2 , 21.0 grams; heat, 1 70 cals.; respiratory 



quotient, 0.87. 



'Gigon, Arch. f. d. ges. Physiol., 1911, 140, p. 509. 



'Sample included amount for 4 hours without food preceding experiment. 

 'Heat eliminated corrected for change in body-weight, but not for change in body-temperature. 

 4 Subject finished eating 21 minutes after beginning of this period. The eating occupied 7 

 minutes. 



