288 FOOD INGESTION AND ENERGY TRANSFORMATIONS. 



the heat output of from 8 to 12 calories per hour for 6 to 12 hours, and 

 that the total effect upon the heat output is not complete in 12 hours. 

 The period of maximum rise in metabolism probably occurs within 

 the first 4 hours, although a considerable increase may be found for a 

 much longer period. 1 



GLIDINE. 



In May 1910, five experiments were made with a vegetable protein 

 substance called "glidine," 2 which is claimed to be the gliadin of wheat. 

 As will be seen from table 50 (page 124), this food material had a 

 protein content of approximately 87 per cent. An unfortunate feature 

 of the experiments with glidine was the fact that the subjects found 

 it almost impossible to eat any considerable amount. The largest 

 amount taken was 70 grams, which was used in two experiments; in 

 three experiments the subject took only 45 grams. All the observations 

 were made with the chair calorimeter. The statistical data not included 

 n the tables or the discussion of the experiments are given here : 



L. E. E., 8 h 40 m a. m. to 3 h 19 m p. m., May 3, 1910. 59.6 kilograms. 2 basal 

 periods. Basal periods ended 10 h 40 m a. m.; food periods began Il h 19 m a. m. 

 Subject unable to take a large amount of glidine without nausea. Urinated 

 6 h 30 ra , 8H7 m , 10 h 45 m a. m., 12 h 19 m , 2 h 19 m , 3 h 19 m p. m. Drank 85 grams water 

 12 h 19 m p. m. Asleep 12 h 04 ra p. m. to 12 h 12 m p. m. and I h 32 m p. m. to 2 h 08 m 

 p. m.; restless at other times. Rectal thermometer slipped out of position 

 in third food period; temperature records not available after 12 h 19 m p. m. 

 Basal periods: body-temperature, 36.90, 36.81, 36.93 C.; pulse rate, 56; 

 respiration rate, 16. Food periods: body-temperature, 36.92, 36.94 C.; 

 pulse rate, 55; respiration rate, 17. 



L. E. E., 8 h 31 m a. m. to 2 h 13 p. m., May 11, 1910. 59.2 kilograms. 2 

 basal periods. Fasting periods ended at 10 h 31 m a. m.; food periods began 

 at Il h 13 m a. m. Subject defecated and urinated at 6 h 45 m a. m.; urinated at 

 10 h 31 m a. m. and 2 h 15 m p. m. In first part of first basal period, there was a 

 decided movement and subject was cautioned to keep quiet. Asleep at end 

 of period; awakened at beginning of next period. Rectal thermometer not 

 used after I h 17 m p. m. Basal periods: pulse rate, 56; respiration rate, 17. 

 Food periods: pulse rate, 57; respiration rate, 18. 



J. J. C., 9 h 31 m a. m. to 4 h 43 m p. m., May 9, 1910. 64.5 kilograms. 2 basal 

 periods. Basal periods ended Il h 31 m a. m.; food periods began 12 h 43 m p. m. 

 Subject urinated 6 h 45 m , Il h 36 m a. m., 3 h 53 m , 4 h 55 m p. m. Asleep Il h 10 m a. m., 

 I h 28 m p. m., I h 48 m p. m. and was awakened. Basal periods: body-tempera- 

 ture, 36.6, 36.69, 36.7 C. ; pulse rate, 60 ; respiration rate, 19. Food periods : 

 body-temperature, 36.79, 36.78, 36.80, 36.77, 36.85 C.; pulse rate, 59; 

 respiration rate, 19. 



J. R., 8*38 m a. m. to 3 h 22 m p. m., May 5, 1910. 70.1 kilograms. 2 basal 

 periods. Basal periods ended 10 h 38 ra a. m.; food periods began Il h 22 m a. m. 

 Urinated 7 a. m., 10 h 40 m a. m., 3 h 30 m p. m. Very sleepy during greater part 



'It is of interest to note here that Aub and DuBois, in a recent research, found larger increases in 

 the metabolism following the ingestion of beefsteak with abnormal individuals (a dwarf 

 and a legless man) than with normal individuals of greater weight and body-surface 

 area. (Aub and DuBois, Arch. Intern. Med., 1917, 19, p. 840.) 



'Street, Ann. Rept. Conn. Agr. Exp. Sta., 1913. 



