70 



ON THE FATE OF THE HUMAN EMBRYO IN TUBAL PREGNANCY. 



No. 298. 



(Dr. Pearce, Albany, N. Y.) 



Ovum about 4 mm. in diam. 



(Plate 5, fig. 3.) 



"I am sending a Fallopian tube removed at an operation 

 on March 13. The tube shows rupture over an hemor- 

 rhagic swelling. The clinical diagnosis is rupture of an 

 ectopic pregnancy. It is from a woman, age 26, married, 

 who states that the last menstruation was 3 weeks before 

 the operation. The surgeon is positive that it is a case of 

 ectopic pregnancy. I am not so sure of the diagnosis." 



On examination two nodules were found, each about 

 10 by 6 mm., one hemorrhagic, the other with hemorrhagic 

 walls and villus-like bodies on it. The second body had 

 a lumen the coslom (?). Neither contained any trace 

 of an ovum. The ends of the rupture were then cut into 

 serial sections, and in one of them the remnants of the 

 ovum were found. It is about 4 mm. in diameter, com- 

 posed of small fibrous villi surrounded by trophoblast and 

 blood. Some of the villi have been invaded by leucocytes. 



No. 307. 



(Dr. H. C. Coe, New York.) 



Pathological embryo, 20 mm. long. 



One ovary and hemorrhagic ovum, 40 mm. in diameter, 

 and a distorted embryo, 20 mm. long, were received. 

 Sections were made through the tube-cell, chorion, and 

 embryo. The hemorrhagic mass consists of blood through 

 which are scattered long fibrous villi and mucous strands 

 richly laden with round cells. They seem to grade with 

 each other, thus showing all stages of degeneration of the 

 chorion. The embryo is thoroughly dissociated and there 

 are secondary changes in the cartilages, bones, and con- 

 nective tissues. It must have been strangulated when the 

 villi of the chorion ceased to supply it with nourishment. 



No. 314. 



(Dr. R. M. Pearce, Albany, N. Y.) 

 Pathological embryo, CR 24, NL 18 mm. 



Clot 



Embryo removed from a gestation sac of a tubal preg- 

 nancy; the fetus under 3 cm. in length. 



The embryo had been placed in formalin immediately 

 after the operation. Serial sections show that it must have 

 been dead for some time before the operation, as the tissues 

 are macerated. In the connective tissues there are signs 

 of dissociation and infiltration. Head small and atrophic. 



No. 324. 



(Professor Brodel, Baltimore, Maryland.) 



Pathological embryo, 3.5 mm. long. Ovum hemorrhagic 

 and fleshy, measures 45X45X22 mm. Its walls are thin 

 and lined with the amnion. Villi few in number, rami- 

 fying through the blood clot; some fibrous, being rich in 

 cells; others show mucoid degeneration. There is very 



j. :i. Figure of the embryo found within specimen No. 

 324. X 7 times. (Drawn by Max Brodel.) 



little trophoblast left. At certain points small knobs of 

 syncytium are present, especially along the main wall of 

 the chorion. It appears as if a renewed effort were being 

 made to produce villi to take the place of those degen- 

 erated. 



Collapsed ovum 

 , ; with embryo 



FIG. 2. Figure of the distended tube of No. 324, with an outline of the ovum surrounded 

 by the blood riot indicated with stipple. X 1/1. Drawn by Brodel. 



