HISTOLOGY OF -mi.; POISOX-CI.AXDS OF Hl'FO AOUA. 



BIBLIOGRAPHY. 



ll. |ill\ -I'll I 'helllle 



Tin' iiiiisnns cif the 

 nirn. AIIIIT. Med. 



ABDEUHALDEN, K. 1909. Lehrbuch 

 Berlin. I'll c<l., 353. 



AIIKI.. .1. .!., and I). 1. MACHT. 1911 

 tropical toad Bufn HI;IHI. 

 A ISM., May 27, vi, 1531-30. 



1912. Two crystalline pharmacological agents ob- 

 tained from the tropical toad Hitfu IKJMI. .loimi. 

 rhariuaci.l. and Exper. Tlicr.. in. No. :; .l;m 

 319-377. 



AcKI-JRM A\x, I). 191(1. ["eher ilrll baktenelleii Alil.au (Irs 



Histidins. Zeitschr. f. physiol. < 'hemie, i.x\ . .Mi.Y 



BARGER, G., and G. S. WAI.POI.K. 190.x. Isolation of tin- 

 principles of putrid meat, .lourn. Physiol., 19(19. 

 xxxvin. 343. 



BAROEH, G., and H. H. DALK. 19(19. I'eher Muttcrkorn. 

 Arch. f. cxpcr. Path. u. Pharmakol., LXI, 113. 



BRISTOL, ('. L., and G. W. BARTELMEZ. 190S. The poison 

 glands of Bufo agua. Science, xxvn, No. Ii9(i, 4.1.1. 



BUDGETT, J. S. 1*99. Notes on the Batrachians of the 

 Paraguayan Chaco, with ol servations on tln-ir 

 breeding habits aMd development, especially with 

 regard to Phylomedusa hypochondrealis Cope; also 

 a description of a new genii-. Quart, .lnurn. 

 Microse. Se.. 42, 3o.v :;.;*. 



( 'AI-\IF:I.S, G. lx,s;>. Ktude hiatologique des gjandes a venin 

 du crapaud, et recherchcs sur les moditieal ions 

 apportees dans leur evolution par I'exeilation clec- 

 trii|iie de I'aninial. Arch, de I'liy-., Tome I. .'!' 

 series, 326-62. 



COBRENT CoMMI-.vr. 1911. ll\dro\plicn\lell,\ l.imiii \u 

 animal poison. .luuin. A. M. A., I.MI, Xo. I. H, 



I HERSON, K. L. 19(12. Ueber das Auf treten von Oxypheny- 

 hithylamin hei I'ankreas\ erdiiniin<! und uliei 

 ('ennentative CO,. Al>spall iinji. licit r. ( 'h.-ui |'|i\ - 

 siol. u. Path., 1. .Mil .Mill. 



ESTERLY, < '. ll. 19(11. The -Irueture and reeneral ion of 

 the poison [dands of Plethedon. l'ni\. of Cal. 

 Pill), /oril., l, X... 7. 227 211.-,. 



GUGGENHEIM M. Ull:!. Proleinnveue \rnine. Thcrapi ii 



tische Monatsliclte. lid. 27, .Mis 

 HENZE, N. 1913. p. Oxyplipnylath.\laiiiin, das Speiehel 



driiseiidift der Cephalopoden. Zeit-ehr. f. phy-iol. 



( 'Ill-Ill., XX.\\ II, .11. 



HDI.KKR, DAVENPORT. 1914. Anueliiiid movements in the 



eorial melanophoreS of linnn. \mei-. .lourn. Anal., 



16, No. 2, 237 -2.ML 

 .MlHSE, E. F. 1909. The culaneou- -land- .it eominon 



toads. Anii-r. .lourn. Anal.. i\, 321 :;i.n. 

 SEECK, O. 1891. Ueln-r die Hautdriisen einiyer Amphiliien. 



Dorpat. Iiiauj;. Dissert. 

 \Viuss, (I. Isys. I'eher die Haiitdriiscn von Biifn cinereus, 



Arch. fiir. mikr. Anal., lid. 42i:i, 1(1.1 423. 



WlKl'll(;W>KI, \V. 1914. I'elier Kli'itl-ll^ift. " I .ol .,-." H, |. 1)2. 



1-3. 



</. </., developing glands. 



///. (/.. mucous glands. 



'/v/ . i^laMil- undergoing absorptiG 



parotid ylaMil. 



liattelies of mature yhnid-. 



gland duet. 



gland collar. 

 !/. a., gland acinus. 



secreti 



: nuclei. 

 secretion. 



EXPLANATION OF PLATES. 



Ki:v 



l-'mrui-; REFERENCES. 



a. N.. layer of epinephrin ci'MtainiMi: 



secretion. 



m., muscular la\'er. 

 t. /)., epidermis. 



c. /.. outer loose la\'er of the eutis. 

 s. <-. stratum compactum cutis. 

 /. /., inner loose layer of the cutis. 

 /'., /.me ol the inner loose layer of 



the cutis ahoul the gland 



acinus. 



melanophores. 



vertical Inindles of eonnectu e- 



tissue fibers. 

 ehromaffin cells. 

 , sympathetic gaUL-lion cell-. 

 \ena r.'H a 



a. c., inter-renal system. 

 . '"., adrenal system. 



r., 



I). 6., 



c. ., 



PLATE I. 



Fit,. 1. Bufo iiyua, photograph of an adult male, sliuwiiif; the variation in tone of (lie ventral anil dorsal integument , 

 and the warty appearance of the animal. The hu^e parotid glands (/<;/.) are shown In-hind the tympanum 

 and the pits into which the gland-ducts open are easily visible. 



Fi<;. -. Section through the parotid gland of an adult male toad (B.ojita). Photoraicrogi'aph. Xln. The picture 

 shows four mature fjlan.1 acini lying embedded in the inner loose stratum of the corn mi and the depth of the 

 cutis vera caused by their presence. These elands are full of secretion, ready for discharge. At (he extreme 

 left of the picture arc the remains of an old discharged gland which is rapidly undergoing resorption, The 

 thickening of the cutis is entirely due to an hypertrophy of the inner loose layer. 



FK; :;. Section Ilirough the parotid glands to show the arrangement of the connect ive-t issue libers in the cut is vera. 

 Celloidin-iron hematoxylin stain. Photomicrograph. X20. The photograph slums the division of I he 

 cutis into three layers, the outer loose layer lying just beneath the epidermis and separated from tin 

 inner loose layer by the stratum compact urn. The honeycomb arrangement of the inner loose layers is very 

 plain, two layers of horizontal fibers above and below the gland acini, which are eonneeteil by bundles made 

 of vertical fiber strands. In the plane dividing the outer loose layer from the stratum compaelum lie the 

 eorial melanophores (2). ' The three glands shown in this picture (</. . ;/,) have been partially emptied and 

 one of them is undergoing resorption. 



