244 RETROGRADE Sect. XXIX. 3. */ 



Phrlof. Tranf. v. 59. p. 392. and as no ether vefiels open intoit be - 

 fides thefe' and the ureters, it feems evident, that the unnatural 

 urn;;, produced as above defcribed,when the ureters were tied, or 

 the kidneys obliterated, was carried into the bladder by the retro- 

 grade motions of the urinary branch of the lymphatic fyflem. 



Tire more certainlyto a/certain theexiftenceof another commu- 

 nication between the ftomachand bladder, befidesthatof the circu- 

 lation, thefoilowingexperiment was made, to which I mult beg your 

 nt attention : — A friend of mine (June 14, 1772) orMrink- 

 ing repeatedly of cold ftnafl punch, till he began to be intoxica- 

 ted, made a quantity of colourlek urine. He then drank about 

 two drams of nitre diflolved in fome of the punch, and ate about 

 twenty (talks of boiled afparagus : on continuing to drink more 

 of ihf punch, the next urine that he made was quite clear, and 

 without fmeil ; but in a little time another quantity was made, 

 which was net quite fc colourlefs, and had a ltrong fmell of the 



paragus : he then loft about four ounces of blood from the arm. 



The fmell of afparagus was not at all perceptible in the blood v 

 rteither when freih taken, not the next morning, as myfelf and 

 two others accurately attended to ; yet this fmell Was ftrongly 

 perceived in the urine, which was made juft before the blood 

 was taken from his arm. 



Some bibulous paper, moiftened in the ferum of this blood, 

 and fuffered to dry, fhewed no figrts of nitre by its manner of 

 burning. But fome of the fame paper, moiftened in the urine, 

 and drievl, on being ignited, evidently fhewed the prefence of ni- 

 tre. This Mood and the urine flood fome days expofed to the 

 fun in the open air, till they were evaporated to about a fourth of 

 their original quantity, and began to ftink : the paper, which 

 was then moiftened with the concentrated urine, (hewed the pref- 

 ence of much nitre by its manner of burning •, whilft that moif- 

 tened with the blood fhewed no fuch appearance at all. 



Hence it appears, that certain fluids at the beginning of in- 

 toxication, find another paiTage to the bladder befides the long 

 courfe of the arterial circulation \ and as the inteftinal abforb- 

 ents are joined with the urinary lymphatics by frequent anafto- 

 mcfes, as Hewfon has demonitrated ; and as there is no other 

 road, we may juftly conclude, that thefe fluids pafs into the blad- 

 der by the urinary branch of the lymphatics, which has its mo- 

 tions inverted durin^ the difeafed ftate of the animal. 



A gentleman, who had been fome weeks affected with jaun- 

 dice, and whofe urine was in coniequence of a very deep yellow, 

 took fome cold fmall punch, in which was dilTolved about a 

 dram of nitre •, he then took repeated draughts of the punch, 

 and k*pt himfelf in a ccol room, till on the approach of flight 



intoxication 



