, a RETROGRADE Sect. XXIX. 4. 9, 



26. — Water reduced to fourteen pints. 



28. — Water thirteen pints : he continues the opium, and 

 takes four fcruples of the refm for a dofe. 



February 1. — Water twelve pints. 



4. — Water eleven pints : twitchings lefs ; takes five fcruplc 

 for a dofe. 



8. — Water ten pints : has had many ftools. 



12. — Appetite lefs, : purges very much. 



After this the refm either purged him, or would not ftay ori 

 his ftomach •, and he gradually relapied nearly to his forA 

 condition, and in a few months funk under the difeafe. 



October ? t , Mr. Hughes evaporated two quarts of the water, 

 and obtained from it four ounces and half of a hard and brittle 

 faccharine mafs,' like treacle which had been fomc time boiled. 

 Pour ounces of blood, which he took from his arm with defign 

 to examine it, had the common appearances, except that the fe- 

 rum refembled cheefe-whey ; and that on the evidence of four 

 perfons, two of whom did not know what it was they tailed, thf 

 fe rum had a falttflj tnjle. 



From hence it appears, that the faccharine matter, with which 

 the urine of thefe patients fo much abounds, does not enter the 

 blood-veilels like the nitre and afparagus mentioned above ; but 

 that the procefs of digeftiori refembles the proceft of the ger- 

 minajjon of vegetables, or of making barley into malt ; as the 

 vaft quantity of fugar found in the urine muffc be made from 

 the food which he took (which was double that taken by others)^ 

 land from the fourteen pints of frriall beer which he drank. And, 

 fecondly, as the ferum of the blood was net fv/eet, the chyle ap- 

 pears to have been conveyed to the bladder without entering the 

 circulation of the blood, lince fo large a quantity of fugar, as 

 was found in the urine, namely, twenty ounces a day, could not 

 have previouily exiiled in the blood without being perceptible to 

 the tafte. 



November 1. Mr. Hughes diiTolved two drams of nitre in a 

 pint of a decoclionof the roots of afparagus, and added to it two 

 ounces of tincture of rhubarb : the patient took a fourth part 

 of this mixture every five minutes, till he had taken the whole. 

 — In about half an hour he made eighteen ounces of water, 

 which was very manifeftly tinged with the rhubarb j the fmelj 

 of afparagus was doubtful. 



He then loft four ounces of blood, the ferum of which war, 

 not fo opaque as that drawn before, but of a yellowifh call, as 

 the ferum of the blood ufuaily appears. 



Paper, dipped three or four times in the tinged urine and dri- 

 ed again, did not fcintillate when it was fct on fire ; but when 



the 



