316 DISEASES Sect. XXXItl. 2. io. 



three or four fuch punctures were made in each of their arms, 

 and the blood was ufed in its fluid Mate. 



" As the appearances in all thefe patients, as well as in myfelf, 

 were fimilar, I (hall only mention them in general terms. 

 March 13. A flight fubcuticular difcoloration, with rather a 

 livid appearance, without forenefs or pain, was vifible in them 

 all, as well as in my own hand. 15. The difcoloration fome- 

 what lefs, without pain or forenefs. Some patients inoculated 

 on the fame day with variolous matter have confiderablc inflam- 

 mation. 17. The difcoloration is quite gone in them all, and 

 from my own hand, a dry mark only remaining. And they 

 were all inoculated on the 1 8th, with variolous matter, which 

 produced the difeafe in them all." 



Mr. Power afterwards obferves, that, as the patients from 

 whom the blood was taken had the difeafe mildly, it may be 

 fuppofed, that though the contagious matter might be mixed 

 with the blood, it might (till be in too dilute a ftate to convey 

 the infection ; but adds at the fame time, that he has diluted 

 recent matter with at leaft five times its quantity of water, and 

 which has itill given the infection ; though he has fometimes. 

 diluted it fo far as to fail. 



The following experiments were inflituted at my requeit by 

 my friend Mr. Hadley, furgeon in Derby, to afcertain whether 

 the blood of a perfon in the fmall-pox be capable of communi- 

 cating the difeafe. "Experiment lit. October iSth, 1793. I 

 took fome blood from a vein in the arm of a perfon who had 

 the fmall-pox, on the fecond day of the eruption, and introdu- 

 ced a fmall quantity of it immediately with the point of a lancet 

 between the fcarf and true Ikin of the right arm of a boy nine 

 years old in two or three different places •, the other arm was 

 inoculated with variolous matter at the fame time. 



" 19th. The punctured parts of the right arm were furround- 

 ed with fome decree of fubcuticular inflammation. 20th. The 

 inflammation more confiderable, with a flight degree of itching, 

 but no pain upon prelTure. 2 lit. Upon examining the arm 

 this day with a lens, I found the inflammation lefs exlenfivc, 

 and the rednefs changing to a deep yellow or orange-colour. 

 22d. Inflammation nearly gone. 23d. Nothing remained, except 

 a flight difcoloration and a little fcurfy appearance on the punc- 

 tures. At the fame time the inflammation of the arm inoculated 

 with variolous matter was increafing fall, and he had the difeafe 

 mildly at the ufual time. 



" Experiment 2d. I inoculated another child at the fame 

 time and in the fame manner, with blood taken on the rirft day 

 of the eruption 5 but as the appearance and effects were fimilar 



to 



