U 1NCITANTIA. Art. fat. a. i. 7 



en, the pain is not relieved, till the debility comes on after the 

 ftimulus ceafes to act -, for then after the greater flimulusof t) 

 opium has exhauftcd much of the fenforial power, the lefs ftim- 

 ulus, which before caufed the pain, does not now excite the part 

 into unnatural action. 



In thefe cafes the ftimulus of the opium firft increafes the pain; 

 and it fome times happens, that fo great a torpor follows, as to 

 produce the death or mortification of the affected part ; when* 

 the danger of giving opium in inflammatory difeafes, efpeciallv 

 in inflammation of the bowels ; but in general the pain returns 

 with its former violence, when the torpor above mentioned 

 ceafes. Hence thefe pains attended with inflammation are beft 

 relieved by copious venefeetion, other evacuations, and the clafs 

 of medicines called torpentia. 



7. Thefe pains from excefs of motion are attended with in- 

 creafed heat of the whole, or of the affected part, and a ftrong 

 quick pulfe 5 the pains from defect of motion are attended with 

 cold extremities, and a weak pulfe ; which is alfc generally more 

 frequent than natural, but not always fo. 



8. Opium and alcohol are the only two drugs, we are much 

 acquainted with, which intoxicate ; and by this circumftance 

 are eaflly diflinguifhed from the fecernentia and forbentia. 

 Camphor, and cicuta, and nicotiana, are thought to induce a 

 kind of intoxication *, and there are many other drugs of this 

 clafs, whofe effects are lefs known, or their dofes not ascertain- 

 ed *, as atropa belladonna, hyofcyamus, ftramonium, prunus 

 laurocerafus, menifpermum, cynoglofium, fome fungi, and the 

 water diftilled from black cherry-flones ; the laft of which was 

 once much in ufe for the convulfions of children, and was faid 

 to have good effect ; but is now improvidently left out of our 

 pharmacopoeias. I have known one leaf of the laurocerafus, 

 (hred and made into tea, given every morning for a week with 

 no ill confequence to a weak hyfteric lady, but rather perhaps 

 with advantage. 



It is probable, that other bitter kernels, as thofe of horfe-chef- 

 nuts, and of acorns, sefculus hippocaftanum, and quercus robur, 

 may poffefs fomewhat of an intoxicating quality } and by this 

 kind of ftimulus, as well as by their bitter part, may be ufed to 

 prevent the paroxyfm of an ague, if adminiftered an hour be- 

 fore the expected accefs of it, as is lately afhrmed by Dr. Fuchs 

 of Jena ; who fays, an extract prepared from the ripe kernels of 

 the horfc-chefnut acts like an extract of Peruvian bark ; and 

 Ids that the bark alfo of this tree is ufed with fuccefs inftead 

 of the Peruvian bark. 



The pernicious effects of a continued ufe of much vinous 



fpirit 



