The Parasitology of Pyorrhoea alveolaris. 197 



addition is to be strongly recommended. We have not found 

 emetine to be of the slightest value in treatment, and, although at 

 times the amoebae may show a decrease in numbers during emetine 

 treatment, in our experience this is rare, and they invariably 

 appear again. Isolation and culture of the spirochsetes has not up 

 to the present proved entirely successful, but is being pursued, as 

 is also the endeavour to cultivate the Entamceba gingivalis. (So 

 far we have found it impossible to keep this parasite alive for any 

 length of time, although if placed on the special jellies, and 

 incubated anaerobically at 37° C, it will often be found alive at 

 the end of three or four days. Whether any multiplication takes 

 place under such conditions we have not yet settled, although on 

 several occasions we think there was some increase. Ultimately 

 the bacterial growth completely inhibits the amoebae, and up to 

 the present we have not been able to surmount this difficulty.) 



Our very best thanks are due to Dr. H. M. Woodcock, of 

 London University, who throughout has taken great interest in 

 the research, and who has given us very much help in criticizing 

 and making many valuable suggestions. 



Bibliography. 



1. Bass & John. — Alveodontal Pyorrhoea. Saunders & Co., 1915. 



2. Cropper & Drew. — Researches into Induced Cell Reproduction in 



Amoebae. London : J. Murray, 1914. 



3. Woodcock & Lapage. — Proc. Roy. Soc, Ser. B. Ixxxviii. (1915) p. 353. 



4. Thomson, J. G. & D.— Proc. Roy. Soc. Med., vii.No. 9. 



5. Pbnfold, Woodcock & Drew — Brit. Med. Journ., May 20, 1916. 



