MKMOIKS OF TITE NATIONAL ACADEMY OF SCIENCES. 



9 



Blood and a normal salt solution containing 2 per cent venom, equal parts. In this mixture 

 the nuclei of the erythrocytes were quite distinct. In ninety six hours the corpuscles were broken 

 down. 



In the weaker dilutions used the same effect was noted, as in the mixtures of 2 per cent yenom. 



Equal parts of crotalns blood and human blood brought in contact showed no other effect 

 except crenation at the line of contact. 



In these experiments with crotalns blood the most noticeable feature is the slight effect 

 produced upon the blood of the cro talus by its own venom. 



Cisotai.us Blood. 



THE EFFECT OF VENOM UPON THE RABBIT BLOOD. 



The slides of normal blood showed the corpuscles granular and broken down in ninety-six 

 hours. 



When blood and venom, equal parts, were mixed the erythrocytes in a few seconds became 

 small, dark, globular adherent in clumps and showed increased ductility. The leucocytes showed 

 marked ameboid movement. In ninety-six hours the corpuscles began to lose their hemoglobin. 



Blood and a normal saline solution, equal parts. In this mixture there was no change in the 

 corpuscles. In seventy-two hours the corpuscles were entirely broken down. 



Klood and normal saline solution containing 10 per cent venom, equal parts, showed the 

 erythrocytes small, dark, globular aud separate. Leucocytes retained a slight ameboid movement. 

 In forty-eight hours all corpuscles were broken down. The same result was noted in dilutions as 

 high as 0.2 per cent, In dilutions of 1 per cent to 0.01 per cent venom the corpuscles were normal, 

 and in forty-eight hours they were eompletely destroyed. 



