MEMOIRS OF THE NATIONAL ACADEMY OF SCIENCES. 



305 



Table XVIII. — Tnconu and outgo of energy. — Metabolism experiment No. IB. 



EXPERIMENTS XOS. 15-17 — REST. WITH ALCOHOL DIET. 



Siibject. — E. O., who was the subject of No. 12. His weight without clothing was about 71 

 kilograms (156 pounds). 



Occupation during e-eptriment. — Reading, writing, etc., with as little mental and muscular 

 activity as was compatible with comfort. 



Duration. — Preliminary period 4 days, beginning with breakfast January 12, 1890. The 

 series of experiments Nos. 15-17 began at 7 a. m., January 16, and ended at 7 a. m., January 

 22. The whole period was thus 6 days, of which 2 days were given to each experiment. The 

 subject entered the respiration chamber on the evening of January 15. The total time spent in 

 the chamber was thus 7 nights and 6 days. 



Diet. — Ordinary food furnishing, per day, 109 grams of protein and 2,141 calories of energy, 

 and in addition 72.5 grams of absolute alcohol, furnishing 512 calories of energy, making the total 

 energy of the diet 2.653 calories. The alcohol was taken in 6 doses, 3 with the meals and the 

 other 3 between meals and just lief ore retiring. 



In experiment No. 15 commercial ethyl alcohol was added to a sweetened coffee infusion, as 

 in experiment No. 12. To 775.2 grams of coffee infusion were added 45 grams of sugar and 79.8 

 grams of 90.9 per cent commercial ethyl alcohol, making a total of 900 grams of the mixture, 

 containing 782.5 grams of water. 



In experiment No. 16 whisky containing 45.8 per cent ethyl alcohol by weight was used. 

 Instead of adding the whisky to the coffee infusion it was taken with sugar in water. The 

 whisky and sugar were added to the water by the subject within the calorimeter, in the proportion 

 of 158.3 grams whisky, 45 grams sugar, and 696.7 grams water, making a total of 900 grams, 

 containing 782.5 grams of water and 72.5 grams absolute alcohol, as in experiment No. 15. An 

 apparent increase in the alcohol found in the ventilating air current during experiment No. 16 

 led us to believe that some alcohol might be evaporated during the admixture of whisky and 

 water in the apparatus, and in the following experiments the mixture of alcohol with coffee or 

 water was prepared outside, as had been done in all cases previous to No. 16. 



In experiment No. 17 the alcohol was administered in the form of brandy, containing 50.4 per 

 cent alcohol l>v weight. To 711.2 grams of water were added 45 grams of sugar and 143.8 grams 

 of brandy, thus furnishing the .same amount of water and alcohol as in the previous experiments. 

 The alcohol in the whisky and brandy was determined by the usual method of distillation and 

 determination of the specific gravity of the distillate." 



'See Methods of Analysis. U. S. Dept Alt.. Division of Chemistry, Bulletin 4t> i revised), p. 



