THE DUCTLESS GLANDS 423 



and becomes fatty, but it always contains remnants of its 

 lymphoid elements. 



The thymus is derived from the entodermal portion of the 

 branchial clefts, and is at first epithelial in structure. The 

 precise mode in which the transformation into adenoid tissue 

 •occurs is still under discussion. There can be little doubt 

 that the concentric corpuscles are the remains of the original 

 epithelium. 



Hypertrophy of the thymus is often found post mortem in 

 cases of sudden death, most particularly in infants, but occa- 

 sionally also in adults. 



Nothing whatever is known of the functions of the thymus. 

 Extirpation gives rise to no ill effects (35). 



References 



The following is not intended to be a complete bibliography. The literature 

 on various parts of the subject is now of enormous dimensions. 



Papers marked by an asterisk contain abundant references to literature. 



Introduction 



1. Vincent and Harrison, Journ. of Anat. and Physiol., vol. xxxi., 1897, p. 176 ; 



*Lewis, Internat. Monatsschr.f. Anat. u. Physiol, Bd. xx., 1902. 



2. Bernard, Lecons de Physiol. Exper., 1885, t. 1, p. 96 ; Minkowski and Meh- 



ring, Arch.f. exper. Path. u. Pharm., Leipzig, 1890, Bd. xxvi. S. 371 ; Vitzou, 

 Journ. de Physiol, et de Path, gen., 1901, vol. iii. p- 901 ; Shattock and 

 Seligmann, Proc. Roy. Soc, vol. lxxiii. No. 488, Feb. 11, 1904 ; Marshall and 

 Jolly, *Proc Roy. Soc, 1905, and Phil. Trans., 1906. 



(i) The Suprarenal Caflsules 



3. Stilling, Revue de Medecine, Nov. 1870; Kohn, Arch.f. mikr. Anat. lvi. 1900, 



S. 81, etc. 



4. Swale Vincent, Proc. Roy. Soc, vols. lxvi. and lxvii. ; * Internationale Monats- 



schr. f Anat. u. Physiol., 1898, Bd. xv. ; Journ. of Anat. and Physiol., vol. 

 xxxviii. 1904. 



5. Addison, On the Constitutional and Local Effects of Disease of the Suprarenal 



Capsules, London, 1855. 



6. Schafer, * Text-Book of Physiol., vol. i. p. 948, Edin. and Lond. 1898 ; Brown- 



Sequard, C. R. de PAcademie des Sciences, Paris, 1856 ; Arch, generates de 

 Med., Paris, 1856. 



7. Moore and Purinton, Amer. Journ. of Physiol, vol. iv. 1900, p. 57, and vol. v. 



1901, p. 182. 



8. *Swale Vincent, Journ. of Physiol, xxii. pp. Hi and 270, 1897-8. 



9. Blum, Deutsch. Arch. f. Klin. Med., Bd. lxxi. p. 146. 



10. *Drummond,/(»«r«. of Physiol, vol. xxxi. p. 81, 1904. 



11. Oliver and Schafer, Proc of the Physiol. Soc, March 1894, and March 1895 ; 



Journ. of Physiol, 1894 and 1895 ; *Journ. of Physiol, 1895, vol. xviii. 

 p. 230. 



