344 SCIENCE PROGRESS. 



glands and a few of the lower cervical glands, while there 

 were a few nodules in the lungs. 



The third calf was killed in eighty-five days and showed 

 numerous superficial ulcers, especially in the lower part of 

 the ileum and in the caecum, while the caecal and mesenteric 

 glands were also affected, and the posterior mediastinal and 

 lower cervical glands were tuberculous. The lungs showed 

 a few nodules of tubercle, and the lower part of the pleurse 

 showed the characteristic " grapes " of bovine tuberculosis. 

 The last calf was killed in 259 days. Twenty-five nodules 

 were found in the small intestine, and there was tuberculosis 

 of the mesenteric glands and of a few of the retro-hepatic 

 glands, while the posterior mediastinal and the bronchial 

 glands were tuberculous, and the glands below the angle of 

 the jaw on the right side. Besides this there was extensive 

 tuberculous pleurisy in the form of "grapes," the lung tissue 

 itself being unaffected. In the three first calves the channel 

 of infection was through the intestinal tract, and thence it 

 affected the mesenteric glands and subsequently the glands 

 and organs in the thorax. This was frequently observed 

 also in natural tuberculosis in cattle, namely, that from the 

 seat of the infection in the intestine the organs and the 

 thorax are soon affected. In the fourth calf the seat of 

 infection was two-fold : in the small intestine and in the 

 pharynx on the right side. The results in this calf are 

 interesting, as showing that tubercular pleurisy can occur 

 from intestinal infection without the lung tissue itself being 

 involved. The results, therefore, of the feeding ot pigs 

 and calves with tuberculous material, show three chief 

 points, namely, that with a small dose there may be absence 

 of a local lesion at the seat of infection ; that the neigh- 

 bouring lymphatic glands are almost constantly affected ; 

 and that the size of the local lesion may be out ol all pro- 

 portion to the tuberculosis which subsequently develops. 



These results are to some extent explanatory of the 

 cases of tuberculosis which occur in the human being. A 

 few of these may now be referred to. It is seen, both in 

 the pig and calf, that the glands below the jaw are readily 

 affected, especially in the pig, by the ingestion of tubercu- 



