THEORIES OF IMMUNITY. 



ing his views, but that is certainly open to other 

 constructions. 



The most important seems to be that of 

 Madsen upon tetanus. His experiments were 

 carried on in the test-tube, avowedly to avoid 

 any chance of physiological action, and were 

 of extreme interest and importance. He found 

 that in certain cultures of the tetanus bacillus 

 he was able to demonstrate a substance which 

 he called " tetano-lysin," and which was capable 

 of destroying the red-blood corpuscles, and that 

 this might exist side by side with the ordinary 

 w tetano-spasmin." He further showed, by special 

 methods, that an anti-tetano-spasmin could be 

 produced which would act in a manner precisely 

 similar to that of diphtheria antitoxine. 



A most important matter for the support of 

 Ehrlich's theory is the determination of the 

 place where the antitoxine is formed, for if it 

 be supposed that the antitoxine is produced by 

 a specific chemical reaction in the cells, it must 

 also be supposed that this reaction takes place 

 in certain tissue cells and no others. It must 

 be formed in at least some of the fixed cells, 



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