446 SCIENCE PROGRESS. 



may well depend on the quality of the mallein used. Even 

 if this is not the case the experiments only show that non- 

 glandered animals may respond with rise in temperature, 

 and it has repeatedly been noticed that animals suffering 

 with acute respiratory troubles may give a reaction which 

 resembles the specific effect of mallein. 



In veterinary practice tuberculin is freely used as a 

 diagnostic measure for cases of bovine tuberculosis, and 

 Arloing (28) has studied the effect of injections of pneumo- 

 bacillin in suspected pleuro-pneumonia. Neither of these 

 bacterial products appears to possess any therapeutic value, 

 and the same is certainly true for all the various prepara- 

 tions of mallein. The employment of this substance 

 for therapeutic purposes appears useless, but these re- 

 searches have at the same time shown its value as a means 

 of diagnosis in glanders. A considerable literature deals 

 with this question, and Commissions (29) have reported 

 in favour of its use. Even if it is admitted that the 

 experimental work is not absolutely convincing it may be 

 fairly urged that in the majority of cases where the clinical 

 symptoms are obscure, injections of mallein offer the surest 

 test by which doubtful cases can be recognised. 



BIBLIOGRAPHY. 



(1) Abolenski. Archiv f. Veterindrmed., 1894. 



(2) Sacharow. Archiv f. Veterindrwissensch., Bd. i., 1893. 



(3) Kalning. Archiv f. Veterindnvissenschaften, Bd. i., St. 



Petersburg, 1891. 



(4) BABES, V. Archiv f. wissenschaft. u. prakt. Thierheilkunde, 



Bd. xviii., 1892. 



(5) PEARSON. Jour, of Coiup. Med. and Vet. Arch., vol. xii., 



1 89 1 . 



(6) Preusse. Berliner tierdrztl. Wochenschrift, 1891, No. 39. 



(7) Johne. Sachs, vet. Jahresbericht, 1891. 



(8) GUTZEIT. Zeitschrift f. Veterindrkunde, Bd. iv., 1892. 



(9) PREISZ. Deutsche Zeitschrift f. Tiermed. u. vergl. Pathol., 



Bd. xx., Heft 5, 6. 



(10) BONOME and VIVALDI. Riforma Medica, 1892, No. 68. 



Abstract in BaumgarterCs Jahresbericht, 1893. 



(11) MALZEW. Archiv f. Veterindrmed., 1892. 



