712 SCIENCE PROGRESS 



metalloidal ion has a sufficiently large molecular volume, it 

 resembles the bulky elementary ion of sodium or potassium in 

 furnishing ionisable halides (chlorides, bromides, and iodides) 

 and soluble strongly alkaline hydroxides. 



Nowadays, when elementary atoms are regarded as having a 

 composite structure, this synthesis of compound alkali radicals 

 in the manner just indicated is a fact of great significance. 



Conclusions 



The investigations in the wide field of organic derivatives of 

 metals and metalloids on which I have touched so very super- 

 ficially have amply justified themselves in a variety of ways. 



On the theoretic and doctrinal side of chemistry they have 

 proved to be of fundamental importance in establishing the 

 theory of compound radicals. They have greatly enlarged our 

 conceptions of stereo-chemistry and the structure of molecules, 

 and have thrown much additional light on the manifestations of 

 chemical affinity and valency. 



From the practical standpoint these researches have endowed 

 chemists with the Grignard reagents and other synthetic agents 

 of a most general type. 



To the physician they have furnished several valuable series 

 of synthetic drugs in which a close connection can be traced 

 between chemical constitution and physiological action, and the 

 combined chemical and clinical study of these materials has 

 given rise to a new science — " Chemiotherapy." 



At the outset an apparently fantastic development of chemical 

 synthesis, these experimental researches have vindicated the 

 cogency in chemistry of Bamberger's bold assertion, " Ohne 

 Phantasie kommen wir nicht weiter." 



