ioo SCIENCE PROGRESS. 



has been studied by A. E. Wright (Jour. Pathol, and 

 Bacteriol, i. 434), by Lilienfeld (Arch. Physiol., 1892, 

 115; Verh. d. Physiol. Ges., Berlin, 189 1-2, No. 16), 

 and by Halliburton and Brodie (Brit. Med. Jour., March, 

 18 and 25, 1893, also ibid., 1893, ii. 133). In all of these 

 the influence of the work of Wooldridge and Pekelharing 

 is seen. All agree in the importance now attributed to 

 nucleo-albumin, and the idea of a ferment is becoming 

 subsidiary. The blood-platelets, which Lilienfeld shows 

 to consist of nucleo-albumin, seem to be very generally 

 regarded as disintegration products of the colourless 

 corpuscles. Wright specially insists on the important 

 part played by carbonic anhydride in the coagulation 

 process. 



The blood corpuscles have been studied by Bleibtreu 

 (Pfliiger's Archiv, li. 151; Hi. 323), and by Lange 

 {ibid., Hi. 427). These investigators devised an ingenious 

 method of estimating the volume of the corpuscles by 

 estimating the nitrogen by Kjeldahl's method in mixtures 

 of blood and salt solution, and in the serum of the same 

 blood. Their results, however, are invalidated by the 

 erroneous assumption that the salt solutions employed 

 have no solvent or osmotic action on the corpuscles. 

 This is fully pointed out by Hamburger (Ceutr. Physiol., 

 June 17, 1893, and Jan. 24, 1894), who has also ex- 

 tended his observations on the osmotic phenomena of 

 blood corpuscles in relation to acids and alkalies (Du 

 Bois Reymond's Archiv, 1892, 513 ; Pec. Trav. Cheiu., 

 ii. 61). 



The dissociation of oxyhemoglobin in aqueous solu- 

 tions has been afresh investigated by Hiifner (Zeit. 

 physikal. Chem., ii. 794) ; and a number of respiratory 

 pigments in invertebrates, which play the same role as 

 haemoglobin in those animals, have been the subject of 

 numerous papers by A. B. Griffiths ("On Echinochrome," 

 Compt. Rend., cxv. 419; "On Hsemerythrin," ibid., cxy. 

 669 ; " A Colourless Respiratory Globulin in Molluscs 

 Blood," ibid., cxv. 474, 1206). 



Perhaps, however, the most interesting paper on 



