94 SCIENCE PROGRESS. 



Nucleic acid, the organic acid which contains the 

 phosphorus in nucleins, and nucleo-albumins has been the 

 subject of renewed research by A. Kossel and J. Horbac- 

 zewski (Ckem. Centralbl., 1893, jSy, 788). The former 

 has investigated the chemical side of the question, and 

 the latter re-affirms his position on the formation of uric 

 acid from the nuclei of cells. In connection with this 

 subject, it is necessary to allude to an important work by 

 L. Lilienfeld and A. Monti (Zeit. physiol. Chan., xvii. 410), 

 who by the use of ammonium molybdate and a reducing 

 agent (pyrogallol) have been able to demonstrate the 

 presence of phosphorus in the tissues and organs micro- 

 chemically. 



We next come to the investigations which relate to 

 the proteids obtainable from various tissues and organs. 

 C. T. Morner {Zeit. physiol. Ckem.., xviii. 61) has examined 

 the proteids of the crystalline lens ; he finds two globulins 

 which he designates crystallin-a and crystalling, a trace 

 of albumin, and an insoluble albuminoid. In a later 

 paper treating of the other refractive media of the eye 

 (ibid., xviii. 213) he deals especially with their mucinoid 

 constituents. 



The proteids of liver and kidney cells, and of nervous 

 tissues, have been studied by W. D. Halliburton (Jour. 

 Physiol., xiii. 806, xv. 90) ; he devotes special attention to 

 the nucleo-albumins, the substances which Wooldridge 

 termed tissue-fibrinogens. He has introduced a new 

 method of preparing them, and finds that they produce 

 intravascular coagulation, as when prepared by Wooldridge's 

 method, even when freed from all lecithin. L. Liebermann 

 (Prluger's Arckiv, 1. 25, 55, liv. 573) has introduced the 

 term lecithalbumin. This compound he has separated 

 from intestinal epithelium cells, and from kidney cells, by 

 subjecting them to gastric digestion ; the insoluble nuclein- 

 like residue contains, he believes, lecithin in actual 

 combination. 



The proteids of spleen and thyroid are similar to those 

 obtained from other cellular organs. There is, however, 

 this point of interest to be noted, namely, that the colloid 



