ZOOLOGY AND BOTANY, MICROSCOPY, ETC. 295 



Conjugation of Resting Nuclei in an Epithelioma of the Mouse.* 

 E. F. Bashford and J. A. Murray draw attention to the fact that the 

 power of cell proliferation, which has been proved to occur in an epi- 

 thelioma of the mouse (Jensen), is a phenomenon unparalleled in the 

 mammalia. A mass of tumour, 16 lbs. in weight, has been produced by 

 artificially transplanting portions of the original growth and its descen- 

 dants. When portions of the tissue are transplanted to new sites, the 

 tumours which arise are the genealogical descendants of the cells intro- 

 duced, and the growth was studied at successive stages of 24 hours. In 

 a tumour removed on the eighth day, and less than half a split pea in 

 size, conjugation of resting nuclei has been observed. To take a specific 

 case, the nuclei of two adjacent cells are continuous through the cell- 

 wall by a tube-like bridge, in the middle of which a strand of nucleolar 

 substance, with fusiform swellings, in either cell is visible. The cells of 

 this particular case are adjacent to the stroma, and close to the outer 

 surface of the young tumour. 



Behaviour of the Protoplasm in Monocentric Mitoses.f — T. Boveri 

 describes certain peculiarities in the behaviour of the protoplasm of the 

 eggs of sea-urchins which have been shaken after fertilisation. In many 

 cases the effect of this treatment is to inhibit the division of the sperm 

 centrosome, so that the egg contains not an amphiaster with equatorial 

 plate, but a large monaster, to which the chromosomes are joined in a ball- 

 like form. The succeeding behaviour varies, but in the majority he 

 finds that the surface of the egg furthest removed from the sphere shows 

 a very distinct amoeboid movement, which is more marked in proportion 

 to the eccentricity of the latter. All the rest of the surface is com- 

 pletely smooth. In the case of eggs deprived of their yolk-membrane, 

 elongation takes place in the direction of the spindle axis, and, without, 

 a narrowing at the equator division occurs with amoeboid processes be- 

 tween the blastomeres similar to those of monaster eggs. From a con- 

 sideration of these and related phenomena, he inclines to the view that 

 the appearance of the equatorial plates in normal cell division is due to 

 the slight influence of the centrosomes in this region — a negative and not 

 a positive effect. 



The Morphology of the Glands of Bartholin in Mammals.! — 

 H. Rautmann has investigated the occurrence and nature of the glands 

 of Bartholin in ox, sheep, horse, cat and dog, as well as the human 

 subject. He failed to find these in both sexes of the Canidas, a fact not 

 to be explained as due to disappearance during development, for they f are 

 absent in the embryo. In the human female, as in the cow, sheep and 

 cat, they occur in pairs, and relatively strongly developed. In the sheep 

 they are poorly developed, and may be absent on one side or altogether. 

 In the mare, ass, mule and sow they are present in all individuals, in 

 numbers subject to great variation, and arranged in rows in a longi- 

 tudinal direction. The author cannot as yet, owing to the too limited 



* Proc. Roy. Soc. London, lxxiii. (1904) p. 77- 



t S.B. Phys. med.-Ges. Wurzburg, 1903, pp. 12-21. 



X Arch. Mikr. Anai, lxiii. (1903) pp. 461-511 (1 pi.). 



