436 Miscellaneous Intelligence, 



and bit two others, which were also infected ; from these last no 

 further contagion was observed. 



xi. During the period of the inactivity of the virus, there are no 

 morbid alterations observable, either locally or in the general health 

 of the dog thus infected, nor does the lower surface of the tongue 

 ever exhibit vesicles. There exist accordingly no precursory symp- 

 toms as in other contagious diseases. 



xii. The disease generally breaks out within 50 days after the 

 inoculation, or the infliction of the wound. It was never observed 

 at a later period. . • W .^ur > 



xiii. Inoculation or infection from animals affected with fiewse 

 rabies, very often produces the other modifications of the disease, 

 and vice versd ; they are consequently only different forms of one 

 and the same disease. 



xiv. It is an erroneous opinion that healthy dogs are able to dis- 

 tinguish those affected with rabies by the smell ; this is not the case, 

 nor do they abhor food mixed with the secreta or excreta of rabid 

 dogs. — Med. Jour. Ixiii. 460. 



7. On the Development and Growth of Cantharides. Zier.— The 

 flies always deposited their eggs on the smooth sides of the vessel 

 in which they were inclosed ; but it was found requisite that these 

 sides should not be transparent ; so that when glass capsules were 

 used they were covered with black paper, and there the eggs were 

 deposited. Each female produced from 100 to 200 in a small heap. 

 Nothing is more difficult than to observe the transformation of these 

 eggs into larvae, in consequense of the momentary nature of the change. 

 M. Zier knowing about what time to expect the change with certain 

 eggs, waited for and watched them under the microscope, and was 

 fortunate in catching the moment. He first remarked certain slight 

 motions followed by others much stronger and quicker, at one end 

 of the egg^ and instantly it was converted into a living being, a 

 small larva. It was impossible to discover any envelope which 

 might be supposed to be left by the insect ; the whole egg appeared 

 to be vivified. 



The larva is at first colourless and formed of 13 rings, of which 

 the first is the head, the three next have each a pair of feet, by 

 which the insect moves with considerable rapidity, the nine other 

 rings form the body. Two black points on the first rings are the 

 eyes, above is a sort of black antennae, the last ring has two hairs. 

 Almost immediately after the change, the posterior part of the larva 

 acquires a dark tint, which advances gradually to the fifth ring, 

 the fourth and third remain pale, but the second and first become 

 black. 



These small animals move very quickly, and soon leave the place 

 where they were deposited as eggs. When they feel any movement 

 in the neighbourhood, they roll themselves up so as to look like 

 black points. The metamorphosis of all the eggs into larvae, and 



