390 Proceedings of the 



of water for its solution ; but when dissolved in alcohol or an 

 acid, it has the bitter taste of bark. When heated, it does not 

 fuse before decomposition. When analyzed, it gives oxygen, 

 hydrogen, and carbon, the latter being predominant. It con- 

 tains no nitrogen. It dissolves only in small quantity in the 

 fixed or volatile oils, or in sulphuric ether. 



Cinchonine combines with acids, and forms neutral salts, of 

 which the solubility and crystalline form varies with the acid 

 employed. The sulphate of cinchonine is easily crystallized, 

 is moderately soluble, and is composed of 



Cinchonine...*... 100 

 Sulphuric acid ... . 13.021 



The muriate of cinchonine is more soluble, and is com- 

 posed of 



Cinchonine , 100 



Muriatic acid .... 7.9 



The nitrate is uncrystallizable. 



The weight of the atom of cinchonin, calculated from the 

 analysis of the sulphate, is 38.488. 



Gallic, oxalic, and tartaric acid, form neutral salts with cin- 

 chonine, which are very slightly soluble, but are soluble in an 

 excess of acid. M. Vauquelin ascertained that infusion of 

 nut-galls constantly formed an abundant precipitate, when 

 poured into a decoction of good cinchona. This precipitate is the 

 difficultly soluble gallate of cinchonine. 



Cinchonine does not combine with the simple combustible 

 bodies. By the medium of water it converts chlorine and 

 iodine into chloric, muriatic, hydriodic, and iodic acids. 



After having examined minutely the properties of cinchonine, 

 and the substances which accompany it in the grey cinchona 

 we passed to the examination of the yellow bark, (cinchona 

 cordifolia). This substance proved to be extremely analo- 

 gous to the former in its composition. But the base contained 

 in the latter is not exactly the same with the cinchonine y and 



