200 Dr. Anderson on the state in which Fibrin exists in the Blood. 



Mr. Stenhouse exhibited some salts of meconic acid which he had 

 prepared and analysed. 



Slst Jantuiry, 1844, — The President m the Chair. 



Messrs. William Smith and William Wilson were admitted mem- 

 bers of the Society. 



The following paper was read. 



XLVI. — Note on the state in which Fibrin exists in the Blood. By 

 Andrew AlNDErson, M.D., Andersonian Professor of the Institutes 

 of Medicine, 



It has for some time been the general opinion among physiologists, 

 that the fibrin of the blood is liquid during life, and becomes solid 

 only when that fluid dies ; and this opinion is based on the well-known 

 experiment, first performed by Miiller, of filtering frog's blood before 

 its coagulation, and thus obtaining the clot separate from the globules, 

 which remain behind on the paper. At the meeting of the British 

 Association at Glasgow, Dr. A. Buchanan exhibited a method of show- 

 ing the same thing in human blood, by receiving it from the vein into 

 a vessel of serum, in which the globules subside before coagulation. 



The conamon notion of the change which takes place on coagulation 

 has been well expressed as follows : — 



T5ioa«,o i Fluid Serum "i 



riasma ^ p.^^.^ ^ i j^^^^ ^j^^^ 



^^^^^^S^^^loiobules^^-'^iciot / 

 From this opinion there have recently dissented M. Mandl* and 

 * Anat. Microscopique, Art. Sang. 1842. 



