f^ On the Effects of Opium 



Muiutes. Ther. 



f^O. Pulse is now more slow and 



more feeble, not more than 

 240. Animal trembles very 

 much and is less active. 



40. 10. Pulse not more than 216. 

 ^l^ — Pulse very feeble, only 192. 



30. 12. Pulse considerably more fee- 

 ble ; can scarce be counted, 

 yet not more than 1 80. Ani- 

 mal trembles and breathes 

 very laboriously. In this 

 state the animal was left 

 until morning : the fri^o- 

 rific mixture had dissolved 

 during the night, and the 

 thermometer bad rose to 

 50. The pulse of the ani- 

 mal was feeble, but beat 

 240 .in a minute. 



EXPERIMENT 46. 



A full-grown frog, whose heart beat 62 in 

 a minute at 



ir» M. 



iQ^i — Was put into a tin vessel of the 

 •.: temperature of 8". 



2. Frog removed. Heart much more 

 feeble; beats only 26 in a minute. 

 Animal put in again. 



