68 On the Effects of Opium. 



Hours. Minute*. 



little relieved by large draughts 

 af lukewarm milk and water, but 

 continued notwithstanding very 

 severe, for more than three hours. 



EXPERIMENT 41. 



H. M. 



8. 54. Mr. Mackenna, upon an empty 



stomach, took two grains of 

 opium dissolved in a little water. 

 Pulse 78. 



9. — Pulse 80, and considerably more 



full. 

 22. Pulse 82, and continuing still full. 



A sense of heaviness and stupor 



in the head. 

 32. Pulse continues at 82, but rather 



more feeble. 

 54. Pulse fallen to 78, and diminished in 



strength. Sense of languor : Face 



flushed. 

 10. 5. Pulse sunk to 74, but yet somewhat 



full. Two grains more of opium 



were taken. 

 20. Pulse remains at 74 : sense ef lan- 

 guor abated ; a little confusion of 



mind approaching to intoxication. 



