62 On the Effects of Opium 



was compared -, the principal points in which 

 they agree are the following : 



1st. An encreased action of the heart and 

 arteries, succeeding the introduction of the 

 several substances into the stomach of rabbits. 



2d. This encreased action being evident 

 more early in young than in the full grown 

 animals. 



3d. The succeeding diminution occurring 

 sooner in the young, than in the adult 

 animals. 



4th. The more speedy death of the young, 

 than the full grown animals, from equal quan- 

 tities of the several substances taken in. 



5th. The entire destruction of contractility 

 in all the voluntry muscles and a diminution of 

 it, almost amounting to exhaustion in the heart 

 after death, from the action of the several 

 substances introduced into the stomach. 



These experiments, wliich may be con- 

 cluded as positive facts, not only serve to elu- 

 cidate the question, but have a more wide in- 

 fluence ; they lead to an explanation of the 

 defect of appearance of encreased action, 

 when the same substances were applied to the 

 hearts, and injected into the stomach of frogs. 



Before any attention is paid to such expla- 

 nation, we shall continue the analogy some- 

 what further, and notice the most striking of 



