on the Living Sjptem, ^4J 



Hours. Miuutet. 



41. Contractions have returned to their 

 former frequency, but the force 

 greatly diminished. 



The light ventricle was perforated, and 30 

 drops of water injected -, they appeared to make 

 little or no alteration. The contractions had 

 not ceased 51 minutes after this time. 



In these last enumerated experiments, the 

 following similar effects' were observable, from 

 the application of aether, spirits of wine, spiritus 

 volatilis aromaticus and opium. 



1st. Encreased force and frequency of the 

 contraction of the heart upon the application 

 of the above-mentioned powers to that organ. 



2d. A diminution of force and frequency, in 

 the contractions, in the space of two minutes 

 afterwards. 



3d. The same effect, but in a less degree, 

 produced upon the second application of the 

 same substances. 



4th. The entire cessation of motion in the 

 heart when the same substances were injected 

 into the cavity, in a quantity greater than what 

 was applied to the surface of the heart. 



From this last consideration, I am inclined to 

 attribute the <lifferent effects, i. e. the encreased 

 action in the first instance, and the diminished 

 action in tlic second, wliich api^car on the ap- 



