46 On the ILffecls of Opium 



condition witli the foregoing, which was fol- 

 lowed by an encrcasc both of force and fre- 

 quency in the contractions ; after the injection 

 of 30 drops into the cavity of the heart, the 

 same loss of contractility was apparent. 



EXPERIMENT 20. 



The thorax of another rabbit was opened, 

 and after the comoilsions had ceased at 



Hours. Minutes. 



5. 31. Ten drops of water were poured 

 upon the surface of the heart, 

 , whilst contracting with force, but 

 no apparent alteration was pro- 

 duced. 



33. The contractions have not dimi- 



nished in frequency, but the force 

 appears less. 



34. The pericardium was stripped off: 



Contractians greatly augmented 

 by this operation. 

 36. Water applied again, a slight dimi- 

 nution of contractions ensued. 



38. Contractions very frequent, but 



feebler. 



39. A few drops of water applied again j 



a momentary diminution of con- 

 tractions ensued. 



3 



