44 0?i the Effects of Opium 



Hours. Minutes. 



1. 5. Ten drops of the solution (i. e. half 

 a dram of opium to one ounce of 

 water) were poured upon the 

 heart whilst contracting 60. 

 54. Contractions encreascd both in force 

 and velocity, to 78. 



7. Contractions abating of their force 



and frequency, 65. 

 — The pericardium was stripped off. 



8. Solution of opium applied again in 



the same quantity. 



8 J. Contractions visibly encreased to 

 72. 



10. The ventricle was perforated with 

 the point of a knife, the heart 

 stiU contracting with force; thirty 

 drops of the solution were injected 

 into the heart : motion diminished 

 almost instantly, one or two con- 

 tractions appearing after the in- 

 jection of the solution, but not 

 more. The point of a knife and 

 lancet, applied afterwards, did 

 not excite anv motion. 



