¥1 On the Effects of Opium 



ll^urs. Minutes. 



40. Contractility of the heart entirel^^- 

 exhausted : no motion could be 

 excited, either by opium or an}^ 

 mechanical stmiulus. 



EXPERIMENT 15. 



With Water. 



To examine- if the encreased contractions- 

 which followed in the last experiment the ap- 

 plication of opium to th€ heart, were referable 

 to the quantity of opium, or were to be ascribed 

 to the mechanical stimulus of the bulk of the 

 fluid applied; the thorax of another rabbit 

 was exposed, and after the ventricles had 

 ceased to move, the right auricle exhihiting a 

 tremulous motion as in the last. Ten drops of 

 water equal in temperature to the solution 

 were poured on, but without any contraction 

 being excited : It was applied a second time, 

 and with as little effect. 



EXPERIMENT 16. 



With rectified Spirits of Wine. 



The thorax of a rabbit was opened ; after the 

 animal was dead, the heart continued to con- 

 tract with considerable Jorce, 55 in a minute. 



