40 On the Effects of Opium 



effect in experiment 4, was owing to a stlmu^' 

 lant operation, for such would be the applica- 

 tion of water. The temperature of a frog 

 is only 44, the temperature of water was 

 equal to that of a room within doors, which 

 was not less than from 60 to 70. The frequent 

 variations of the pulse which occurred from the 

 struggles of the animal, would likewise greatly 

 diminish the force of any conclusions which 

 might be drawn respecting the effects of any of 

 the powers applied. The only deduction which 

 can fairly be admitted is, that no difference of 

 effect was observable betwixt the application 

 of opium and strong stimuli, sufficient to justify 

 an opinion that these powers had a different 

 operation. 



Rabbits zoere the Subjects of the next 

 Experiments. 



EXPERIMENT 14. 



The Thorax of a full-grown rabbit was 

 6peined, and the heart exposed by the removal 

 of the sternum. The animal was seized with 

 'convulsions, and died in the space of one 

 minute. The contractions of the heart con- 

 tinued, for more than half an hour after. 



