30 0/t,srt:{ie'iEffec(s . v/^ Opium 



Hours. Mhiulos. 



30. Convulsicjns-when the animal is 

 touched, the heart contracts very 

 • '^ fceblyand very slow. 



bstii -50,. Nd^- motion can be excited in the 

 animal by irritating it,' but' the 

 heart still continues to contract. 

 .The .heait Bid not cease, until 27 

 minutes after. 

 4. liT. When the application of a mecha- 

 nical stimulus produced no'effect, 

 . . either upon the heart or any of 



the organs of voluntary motion. 

 : ' :')':r' -. Opium 2 grains. 



EXPERIMENT 2. 



The heart of -another frog w^as exposed in 

 the skme mariner as the preceding: It beat 

 5^ int'a minute'. 



H. M. 



1. 45. Five:, drops of the saiiie solution 

 containing half a grain of opium 

 were poured' upon the heart. An 

 inatanianeaus diminution of mo- 

 tion suoce.eded. 

 48. Heart beats only 30;: the animal 

 .. : ] --stnigf l^^;;>4ol^ptJy :, _tjfe h^aft ex- 

 p.eii.en<^e4 atennipctrary cessation 

 of action (Jiiringr th^ struggles. 



